Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 14/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11741059 | 0.89 | ACHE (0.50) | CHRNB2CHRNB4CHRNA3CHRNA4ACHE | |
| SCHEMBL5747611 | 0.86 | ACHE (0.48) | CHRNB2CHRNB4CHRNA3CHRNA4ACHE | |
| SCHEMBL11735248 | 0.84 | ACHE (0.57) | ACHEALDH1A1 | |
| SCHEMBL6832195 | 0.84 | ACHE (0.67) | CHRNB2CHRNB4CHRNA3CHRNA4ACHE | |
| SCHEMBL11736597 | 0.83 | ACHE (0.57) | ACHEALDH1A1 | |
| SCHEMBL763817 | 0.82 | ACHE (0.59) | CHRNB2CHRNB4CHRNA3CHRNA4ACHE | |
| SCHEMBL16447335 | 0.81 | ACHE (0.44) | CHRNB2CHRNB4CHRNA3CHRNA4ACHE | |
| SCHEMBL10062061 | 0.80 | ACHE (0.67) | CHRNB2CHRNB4CHRNA3CHRNA4ACHE | |
| SCHEMBL10062060 | 0.80 | CHRNB2 (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4ACHE | |
| SCHEMBL11848496 | 0.80 | ACHE (0.61) | CHRNB2CHRNB4CHRNA3CHRNA4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4582526-A | Carbamic acid ester herbicides | HOFFMANN-LA ROCHE INC. (US) | 1986-04-15 | — | — | US | disclosed |