Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30366016 | 0.91 | LMNA (0.68) | LMNAALDH1A1TSHRMAPTMAPK1 | |
| SCHEMBL120124 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL10792640 | 0.89 | LMNA (0.65) | LMNAALDH1A1TSHRMAPTMAPK1 | |
| Acetone SCHEMBL2960216 | 0.86 | LMNA (0.63) | LMNAALDH1A1TSHRMAPTMAPK1 | |
| Cyclohexane SCHEMBL27452018 | 0.84 | LMNA (0.61) | LMNAALDH1A1TSHRMAPTMAPK1 | |
| Chloroform SCHEMBL4677155 | 0.84 | LMNA (0.61) | LMNAALDH1A1TSHRMAPTMAPK1 | |
| Isopropyl Palmitate SCHEMBL10654442 | 0.84 | LMNA (0.85) | LMNAALDH1A1TSHRMAPTMAPK1 | |
| SCHEMBL3760781 | 0.83 | LMNA (0.53) | LMNAALDH1A1TSHRMAPTMAPK1 | |
| Butyric Acid SCHEMBL28683379 | 0.83 | LMNA (0.59) | LMNAALDH1A1TSHRALOX15FFAR3 | |
| Carbamic Acid SCHEMBL27876791 | 0.83 | LMNA (0.59) | LMNAALDH1A1TSHRMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4585785-A | HYPOTENSIVES, ANTIDEPRESSANTS | A. H. ROBINS COMPANY, INC. (US) | 1986-04-29 | — | — | US | disclosed |
| US-4452809-A | ANTIARRHYMIA, HYPOTENSIVE AGENTS | A. H. ROBINS COMPANY, INC. (US) | 1984-06-05 | — | — | US | disclosed |