Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL120124 | 0.93 | — | — | |
| SCHEMBL30366016 | 0.93 | LMNA (0.68) | LMNAALDH1A1TSHRMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL10792640 | 0.91 | LMNA (0.65) | LMNAALDH1A1TSHRMAPTMAPK1 | |
| Acetone SCHEMBL2960216 | 0.88 | LMNA (0.63) | LMNAALDH1A1TSHRMAPTMAPK1 | |
| Chloroform SCHEMBL4677155 | 0.86 | LMNA (0.61) | LMNAALDH1A1TSHRMAPTMAPK1 | |
| Ether SCHEMBL10839845 | 0.84 | LMNA (0.59) | LMNAALDH1A1TSHRMAPTMAPK1 | |
| Butyric Acid SCHEMBL28683379 | 0.84 | LMNA (0.59) | LMNAALDH1A1TSHR | |
| Carbamic Acid SCHEMBL27876791 | 0.84 | LMNA (0.59) | LMNAALDH1A1TSHRMAPTMAPK1 | |
| Butane SCHEMBL20558824 | 0.83 | LMNA (0.68) | LMNAALDH1A1TSHRMAPTMAPK1 | |
| Acetic Acid Methyl Ester SCHEMBL11403378 | 0.83 | LMNA (0.57) | LMNAALDH1A1TSHRMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1824315-B | Synergistic therapeutic compositions and methods | PFIZER | 2011-01-12 | — | — | CN | disclosed |
| CN-101156949-A | Synergistic therapeutic compositions of angiotensin i converting enzyme inhibitors and angiotensin ii antagonists and methods | PFIZER (US) | 2008-04-09 | — | — | CN | disclosed |
| CN-100358578-C | Process for preparing synergistic composition | PFIZER (US) | 2008-01-02 | — | — | CN | disclosed |
| CN-1915428-A | Synergistic therapeutic compositions and methods | PFIZER (US) | 2007-02-21 | — | — | CN | disclosed |
| CN-1879884-A | Synergistic therapeutic compositions and methods | PFIZER (US) | 2006-12-20 | — | — | CN | disclosed |
| CN-1824315-A | Synergistic therapeutic compositions and methods | PFIZER (US) | 2006-08-30 | — | — | CN | disclosed |
| CN-1502370-A | Synergistic therapeutic compositions and methods | — | 2004-06-09 | — | — | CN | disclosed |
| CN-1307901-A | Synergistic therapeutic compositions and methods | PFIZER (US) | 2001-08-15 | — | — | CN | disclosed |
| CN-1065140-C | Synergistic therapeutic compositions and methods | PFIZER (US) | 2001-05-02 | — | — | CN | disclosed |
| CN-1056426-A | Synergistic therapeutic compositions and methods | PFIZER (US) | 1991-11-27 | — | — | CN | disclosed |