Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | CNR2 | P34972 | 2/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.48 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.48 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.41 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50925 | 0.87 | KDM4E (0.58) | KDM4EHPGDALDH1A1CNR2CNR1 | |
| SCHEMBL9829849 | 0.81 | CLEC4M (0.56) | KDM4EHPGDALDH1A1CNR2CNR1 | |
| SCHEMBL16597393 | 0.80 | KDM4E (0.52) | KDM4EHPGDALDH1A1CNR2CNR1 | |
| SCHEMBL7509122 | 0.79 | KDM4E (1.00) | KDM4EHPGDALDH1A1CNR2CYP1A2 | |
| SCHEMBL395847 | 0.79 | KDM4E (0.62) | KDM4EHPGDALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL3182648 | 0.79 | CNR1 (0.48) | KDM4EHPGDALDH1A1CNR2CNR1 | |
| SCHEMBL9893958 | 0.78 | KDM4E (0.61) | KDM4EHPGDALDH1A1CYP1A2HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL28187483 | 0.78 | ALDH1A1 (0.97) | KDM4EHPGDALDH1A1CNR2CYP1A2 | |
| Hydrochloric Acid SCHEMBL30353212 | 0.78 | ALDH1A1 (0.97) | KDM4EHPGDALDH1A1CNR2CYP1A2 | |
| SCHEMBL12993747 | 0.77 | KDM4E (0.49) | KDM4EHPGDALDH1A1CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4587341-A | BACTERICIDES | BURROUGHS WELLCOME CO. (US) | 1986-05-06 | — | — | US | disclosed |