Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10844289 | 0.89 | CYP19A1 (0.56) | HSP90AA1ALDH1A1CYP26A1CYP19A1 | |
| SCHEMBL10837896 | 0.89 | CYP19A1 (0.56) | HSP90AA1ALDH1A1CYP26A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL10839122 | 0.88 | CYP19A1 (0.55) | HSP90AA1ALDH1A1CYP26A1CYP19A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11107975 | 0.88 | CYP19A1 (0.55) | HSP90AA1ALDH1A1CYP26A1NPC1RAB9A | |
| SCHEMBL10837642 | 0.87 | CYP26A1 (0.46) | ALDH1A1CYP26A1CYP19A1KCNA5MAPT | |
| SCHEMBL11383166 | 0.84 | MEN1 (0.61) | CYP26A1CYP19A1USP2 | |
| SCHEMBL10837886 | 0.84 | CHRM2 (0.61) | ALDH1A1CYP26A1NPC1RAB9ACYP19A1 | |
| SCHEMBL2793637 | 0.79 | ALDH1A1 (0.67) | HSP90AA1ALDH1A1KCNA5USP2KDM4E | |
| SCHEMBL10839014 | 0.79 | OPRD1 (0.48) | ALDH1A1MAPTUSP2 | |
| Hydrochloric Acid SCHEMBL11104489 | 0.78 | OPRD1 (0.47) | ALDH1A1MAPTUSP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4604392-A | 2-substituted benzofuran derivatives useful in treating cardiac arrhythmic, histaminic and tussive conditions | A. MENARINI S.A.S. (IT) | 1986-08-05 | — | — | US | claimed |