Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.46 |
| ▸ | RELA | Q04206 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808840 | 0.97 | THRA (0.46) | THRATHRBNPC1LMNANFKB1 | |
| SCHEMBL10339314 | 0.87 | NPC1 (0.48) | THRATHRBNPC1LMNANFKB1 | |
| SCHEMBL9641385 | 0.87 | NPC1 (0.60) | THRATHRBNPC1LMNANFKB1 | |
| SCHEMBL10335809 | 0.87 | NPC1 (0.60) | THRATHRBNPC1LMNANFKB1 | |
| SCHEMBL10335488 | 0.87 | NPC1 (0.60) | THRATHRBNPC1LMNANFKB1 | |
| SCHEMBL9641057 | 0.87 | NPC1 (0.60) | THRATHRBNPC1LMNANFKB1 | |
| SCHEMBL9406388 | 0.87 | NPC1 (0.60) | THRATHRBNPC1LMNANFKB1 | |
| SCHEMBL9640299 | 0.87 | NPC1 (0.60) | THRATHRBNPC1LMNANFKB1 | |
| SCHEMBL9641105 | 0.87 | NPC1 (0.60) | THRATHRBNPC1LMNANFKB1 | |
| SCHEMBL9406100 | 0.87 | NPC1 (0.60) | THRATHRBNPC1LMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61229842-A | — | — | None | — | — | JP | disclosed |
| JP-S61229842-A | OPTICALLY ACTIVE FLUORINE-CONTAINING ETHER COMPOUND AND LIQUID CRYSTAL COMPOSITION USING SAME | ASAHI GLASS CO LTD | 1986-10-14 | — | — | JP | disclosed |