Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10839963 | 0.97 | THRA (0.48) | THRATHRBNPC1LMNANFKB1 | |
| SCHEMBL9641122 | 0.88 | PTPN11 (0.54) | THRATHRBPTPN11RARBNPC1 | |
| SCHEMBL9641454 | 0.88 | PTPN11 (0.54) | THRATHRBPTPN11RARBNPC1 | |
| SCHEMBL9640174 | 0.88 | PTPN11 (0.54) | THRATHRBPTPN11RARBNPC1 | |
| SCHEMBL9641082 | 0.88 | PTPN11 (0.54) | THRATHRBPTPN11RARBNPC1 | |
| SCHEMBL9640278 | 0.88 | PTPN11 (0.54) | THRATHRBPTPN11RARBNPC1 | |
| SCHEMBL10526187 | 0.87 | NPC1 (0.50) | PTPN11RARBNPC1LMNANFKB1 | |
| SCHEMBL10526181 | 0.87 | NPC1 (0.50) | PTPN11RARBNPC1LMNANFKB1 | |
| SCHEMBL10397802 | 0.87 | THRA (0.48) | THRATHRBPTPN11RARBNPC1 | |
| SCHEMBL10524743 | 0.86 | RARB (0.49) | THRATHRBPTPN11RARBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251335-B1 | HALOGENEN-SUBSTITUTED PHENYL BENZYL ETHER DERIVATIVES, LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM AND OPTICAL SWITCHING ELEMENT | Chisso Corporation (JP) | 1991-04-24 | — | — | EP | disclosed |
| US-4784791-A | LIQUID CRYSTAL COMPOUNDS FOR OPTICAL SWITCHES | CHISSO CORPORATION (JP) | 1988-11-15 | — | — | US | disclosed |
| EP-0251335-A2 | Halogenen-substituted phenyl benzyl ether derivatives, liquid crystal compositions containing them and optical switching element | Chisso Corporation (JP) | 1988-01-07 | — | — | EP | disclosed |