Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10840861 | 0.87 | PGR (0.40) | PGRAR | |
| SCHEMBL9306599 | 0.77 | PGR (0.38) | PGRARPDE7ACES1 | |
| SCHEMBL29117338 | 0.77 | HTR2C (0.38) | PGRARPDE7ACES1 | |
| SCHEMBL2175208 | 0.69 | PGR (0.38) | PGRARCES1 | |
| SCHEMBL29789712 | 0.69 | HTR2B (0.38) | PGRARCES1 | |
| SCHEMBL10838940 | 0.69 | CES1 (0.34) | PDE7ACES1 | |
| SCHEMBL10840373 | 0.68 | PDE7A (0.38) | PDE7A | |
| SCHEMBL10841242 | 0.67 | ALDH1A1 (0.46) | PGRARPDE7A | |
| SCHEMBL29789697 | 0.67 | MAPT (0.50) | PGRAR | |
| SCHEMBL23123274 | 0.66 | PGR (0.39) | PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |