Sugi Predict

Sugi Predict / Compounds / SCHEMBL10840499

SCHEMBL10840499

SCHEMBL10840499

C=CCCCCCCCCCCCC[Si](CC)(CC)CC

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.54
▸ ALDH1A1 P00352 3/20 0.46
▸ ABCC4 O15439 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ LMNA P02545 2/20 0.36
▸ TRPA1 O75762 2/20 0.34
▸ LPAR3 Q9UBY5 2/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32
▸ LPAR2 Q9HBW0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31097218 1.00 TSHR (0.54) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL6890731 1.00 TSHR (0.54) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL14918646 0.98 TSHR (0.50) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL31097224 0.90 TSHR (0.50) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL10843321 0.89 TSHR (0.67) TSHRALDH1A1ABCC4MAPT
SCHEMBL10841407 0.84 TSHR (0.73) TSHRALDH1A1ABCC4MAPT
SCHEMBL10844537 0.84 TSHR (0.73) TSHRALDH1A1ABCC4MAPT
SCHEMBL10841635 0.84 TSHR (0.73) TSHRALDH1A1ABCC4MAPT
SCHEMBL8770117 0.79 TSHR (0.45) TSHRALDH1A1
SCHEMBL10404934 0.79 TSHR (0.31) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4572791-A REACTING ALPHA-OLEFIN WITH DI-OR TRIALKYLSILANE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1986-02-25 — — US disclosed