Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6890731 | 0.98 | TSHR (0.54) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL10840499 | 0.98 | TSHR (0.54) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL31097218 | 0.98 | TSHR (0.54) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL31097224 | 0.92 | TSHR (0.50) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL10843321 | 0.87 | TSHR (0.67) | TSHRALDH1A1ABCC4MAPT | |
| SCHEMBL8770117 | 0.81 | TSHR (0.45) | TSHRALDH1A1 | |
| SCHEMBL10841407 | 0.81 | TSHR (0.73) | TSHRALDH1A1ABCC4MAPT | |
| SCHEMBL10841635 | 0.81 | TSHR (0.73) | TSHRALDH1A1ABCC4MAPT | |
| SCHEMBL10844537 | 0.81 | TSHR (0.73) | TSHRALDH1A1ABCC4MAPT | |
| SCHEMBL8437289 | 0.76 | TSHR (0.46) | TSHRALDH1A1ABCC4MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9651548-B2 | Self-regulating chemo-mechano-chemical systems | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-05-16 | — | — | US | disclosed |
| US-20140349870-A1 | SELF-REGULATING CHEMO-MECHANO-CHEMICAL SYSTEMS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-11-27 | — | — | US | disclosed |
| WO-2013067525-A2 | SELF-REGULATING CHEMO-MECHANO-CHEMICAL SYSTEMS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-05-10 | — | — | WO | disclosed |