Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.70 |
| ▸ | ADRB2 | P07550 | 12/20 | 0.70 |
| ▸ | ADRB3 | P13945 | 13/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11168722 | 0.91 | SLC2A1 (0.72) | SLC2A1ADRB2ADRB3ADRB1ADRA1D | |
| SCHEMBL10890383 | 0.90 | SLC2A1 (0.70) | SLC2A1ADRB2ADRB3ADRB1ADRA1D | |
| SCHEMBL8855251 | 0.89 | ADRB2 (0.75) | SLC2A1ADRB2ADRB3ADRB1ADRA1D | |
| SCHEMBL11464773 | 0.89 | ADRB2 (0.75) | SLC2A1ADRB2ADRB3ADRB1ADRA1D | |
| SCHEMBL11464772 | 0.89 | ADRB2 (0.75) | SLC2A1ADRB2ADRB3ADRB1ADRA1D | |
| SCHEMBL7153896 | 0.88 | SLC2A1 (0.81) | SLC2A1ADRB2ADRB3ADRB1ADRA1D | |
| SCHEMBL28294044 | 0.88 | SLC2A1 (0.81) | SLC2A1ADRB2ADRB3ADRB1ADRA1D | |
| SCHEMBL7153891 | 0.88 | SLC2A1 (0.81) | SLC2A1ADRB2ADRB3ADRB1ADRA1D | |
| SCHEMBL3705430 | 0.88 | SLC2A1 (0.81) | SLC2A1ADRB2ADRB3ADRB1ADRA1D | |
| SCHEMBL10873061 | 0.85 | SLC2A1 (0.78) | SLC2A1ADRB2ADRB3ADRB1ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0070134-B1 | SECONDARY PHENYL ETHANOL AMINES AND THEIR PHARMACEUTICAL USE | BEECHAM GROUP PLC (GB) | 1985-11-13 | — | — | EP | claimed |
| EP-0070134-A1 | Secondary phenyl ethanol amines and their pharmaceutical use | BEECHAM GROUP PLC (GB) | 1983-01-19 | — | — | EP | claimed |
| US-4622342-A | HYPOGLYCEMIC AGENTS, ANTIOBESITY | BEECHAM GROUP P.L.C. (GB) | 1986-11-11 | — | — | US | disclosed |
| EP-0070134-A1 | Secondary phenyl ethanol amines and their pharmaceutical use | BEECHAM GROUP PLC (GB) | 1983-01-19 | — | — | EP | disclosed |