Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10841167 | 0.85 | PARP1 (0.38) | GSK3BMAPK14SCN9A | |
| SCHEMBL10841152 | 0.79 | PARP1 (0.38) | GSK3BMAPK14SCN9A | |
| SCHEMBL9384284 | 0.75 | GSK3B (0.33) | GSK3BMAPK14TGFBR1 | |
| SCHEMBL10843719 | 0.72 | — | — | |
| SCHEMBL4455585 | 0.65 | PDPK1 (0.31) | — | |
| SCHEMBL15769086 | 0.65 | LMNA (0.65) | — | |
| SCHEMBL3230029 | 0.62 | CYP3A4 (0.57) | SCN9A | |
| SCHEMBL14091342 | 0.61 | PDPK1 (0.36) | — | |
| SCHEMBL11184996 | 0.61 | SCN9A (0.38) | SCN9A | |
| SCHEMBL3216284 | 0.60 | GAA (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4581349-A | Certain benzodiimidazoles and their use as radiation sensitizers | UNIVERSITY OF MARYLAND (US) | 1986-04-08 | — | — | US | claimed |
| US-4581349-A | Certain benzodiimidazoles and their use as radiation sensitizers | UNIVERSITY OF MARYLAND (US) | 1986-04-08 | — | — | US | disclosed |