Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3230029 | 0.65 | CYP3A4 (0.57) | — | |
| SCHEMBL10842137 | 0.65 | GSK3B (0.34) | — | |
| SCHEMBL15769086 | 0.64 | LMNA (0.65) | — | |
| SCHEMBL8670138 | 0.60 | KDM4E (0.32) | PDPK1 | |
| SCHEMBL14091342 | 0.60 | PDPK1 (0.36) | PDPK1 | |
| SCHEMBL11184996 | 0.60 | SCN9A (0.38) | — | |
| SCHEMBL8561 | 0.60 | — | — | |
| SCHEMBL7259185 | 0.60 | — | — | |
| SCHEMBL3216284 | 0.59 | GAA (0.50) | — | |
| SCHEMBL2466217 | 0.58 | PDPK1 (0.32) | PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138122-A1 | PURINE DERIVATIVES FURTHER COMPRISING A MERCAPTO-ACYLAMINO GROUP AS NEUTRAL ENDOPEPTIDASE INHIBITORS | NOVARTIS AG (CH) | 2009-11-19 | — | — | WO | disclosed |