Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3022917 | 0.87 | MAPT (0.54) | MAPTALDH1A1GAAPOLBHDAC3 | |
| SCHEMBL10950830 | 0.85 | KDM4E (0.65) | MAPTALDH1A1GAAPOLBHTT | |
| SCHEMBL30764108 | 0.85 | KDM4E (0.65) | MAPTALDH1A1GAAPOLBHTT | |
| SCHEMBL8980104 | 0.84 | MAPT (0.54) | MAPTALDH1A1GAAPOLBHDAC3 | |
| SCHEMBL28711393 | 0.82 | EGFR (0.68) | MAPTALDH1A1GAAHTTLMNA | |
| SCHEMBL28915252 | 0.81 | MAPT (0.51) | MAPTALDH1A1GAAPOLBHDAC3 | |
| SCHEMBL7178423 | 0.81 | EGFR (0.52) | MAPTALDH1A1GAAPOLBHDAC3 | |
| SCHEMBL12189827 | 0.79 | MMP1 (0.65) | MAPTALDH1A1GAAHTTLMNA | |
| SCHEMBL5175949 | 0.79 | MMP1 (0.65) | MAPTALDH1A1GAAHTTLMNA | |
| SCHEMBL7622299 | 0.79 | MMP1 (0.68) | MAPTALDH1A1GAAPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4591597-A | FOR BLOOD SUGAR REDUCTION | CIBA-GEIGY CORPORATION (US) | 1986-05-27 | — | — | US | disclosed |