SCHEMBL3022917

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8980104	0.89	MAPT (0.54)	MAPTALDH1A1GAAPOLBHDAC3
	SCHEMBL10843418	0.87	MAPT (0.50)	MAPTALDH1A1GAAPOLBHDAC3
	SCHEMBL28915252	0.85	MAPT (0.51)	MAPTALDH1A1GAAPOLBHDAC3
	SCHEMBL7178423	0.85	EGFR (0.52)	MAPTALDH1A1GAAPOLBHDAC3
	SCHEMBL12529039	0.82	HPGD (0.59)	MAPTALDH1A1GAAPOLBHDAC3
	SCHEMBL10950830	0.82	KDM4E (0.65)	MAPTALDH1A1GAAPOLBHTT
	SCHEMBL30764108	0.82	KDM4E (0.65)	MAPTALDH1A1GAAPOLBHTT
	SCHEMBL951304	0.82	HPGD (0.59)	MAPTALDH1A1GAAPOLBHDAC3
	SCHEMBL951306	0.82	HPGD (0.59)	MAPTALDH1A1GAAPOLBHDAC3
	SCHEMBL948318	0.82	MAPT (0.59)	MAPTALDH1A1GAAPOLBHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.