Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 6/20 | 0.48 |
| ▸ | RARB | P10826 | 6/20 | 0.48 |
| ▸ | RARG | P13631 | 6/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | RXRA | P19793 | 4/20 | 0.44 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10841056 | 1.00 | RARA (0.48) | RARARARBRARGCYP3A4RXRA | |
| SCHEMBL10846459 | 1.00 | RARA (0.48) | RARARARBRARGCYP3A4RXRA | |
| SCHEMBL10841063 | 1.00 | RARA (0.48) | RARARARBRARGCYP3A4RXRA | |
| SCHEMBL10844148 | 1.00 | RARA (0.48) | RARARARBRARGCYP3A4RXRA | |
| SCHEMBL10846465 | 1.00 | RARA (0.48) | RARARARBRARGCYP3A4RXRA | |
| SCHEMBL10843882 | 0.96 | RARA (0.50) | RARARARBRARGCYP3A4RXRA | |
| SCHEMBL10843886 | 0.96 | RARA (0.50) | RARARARBRARGCYP3A4RXRA | |
| SCHEMBL6909571 | 0.92 | RARB (0.52) | RARARARBRARGCYP3A4RXRA | |
| SCHEMBL7207214 | 0.91 | RARA (0.50) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL7207219 | 0.91 | RARA (0.50) | RARARARBRARGRXRACYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4578498-A | FOR SKIN DISORDERS; REDUCED TOXICITY | BASF AKTIENGESELLSCHAFT (DE) | 1986-03-25 | — | — | US | disclosed |