Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 8/20 | 0.50 |
| ▸ | RARB | P10826 | 8/20 | 0.50 |
| ▸ | RARG | P13631 | 5/20 | 0.50 |
| ▸ | RXRA | P19793 | 10/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | RXRG | P48443 | 2/20 | 0.40 |
| ▸ | HNF4A | P41235 | 2/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207219 | 1.00 | RARA (0.50) | RARARARBRARGRXRARXRB | |
| SCHEMBL10844151 | 0.91 | RARA (0.48) | RARARARBRARGRXRARXRB | |
| SCHEMBL10844148 | 0.91 | RARA (0.48) | RARARARBRARGRXRARXRB | |
| SCHEMBL10846465 | 0.91 | RARA (0.48) | RARARARBRARGRXRARXRB | |
| SCHEMBL10841056 | 0.91 | RARA (0.48) | RARARARBRARGRXRARXRB | |
| SCHEMBL10846459 | 0.91 | RARA (0.48) | RARARARBRARGRXRARXRB | |
| SCHEMBL10841063 | 0.91 | RARA (0.48) | RARARARBRARGRXRARXRB | |
| SCHEMBL10844848 | 0.88 | RARA (0.57) | RARARARBRARGRXRARXRB | |
| SCHEMBL10844843 | 0.88 | RARA (0.57) | RARARARBRARGRXRARXRB | |
| SCHEMBL4666938 | 0.88 | RARA (0.42) | RARARARBRARGRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641759-B1 | Use of aromatic carboxylic derivatives for the preparation of drugs | HOFFMANN LA ROCHE (CH) | 1998-12-09 | — | — | EP | claimed |
| US-6610877-B1 | Treating photo and/or age damaged skin | HOFFMAN-LA ROCHE INC. | 2003-08-26 | — | — | US | disclosed |
| US-5700836-A | TOPICALLY ADMINISTERING TO TREAT PHOTODAMAGED SKIN | HOFFMANN-LA ROCHE INC. (US) | 1997-12-23 | — | — | US | disclosed |