Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.41 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10845056 | 1.00 | LMNA (0.42) | LMNATP53CYP3A4HPGDALOX15 | |
| SCHEMBL10845438 | 0.95 | LMNA (0.50) | LMNATP53CYP3A4HPGDALOX15 | |
| SCHEMBL10846775 | 0.95 | LMNA (0.50) | LMNATP53CYP3A4HPGDALOX15 | |
| SCHEMBL12434159 | 0.94 | NAAA (0.46) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL10843636 | 0.92 | CNR2 (0.41) | TLR2TLR1TLR6CNR1CNR2 | |
| SCHEMBL10847141 | 0.92 | CNR2 (0.41) | TLR2TLR1TLR6CNR1CNR2 | |
| SCHEMBL10571624 | 0.91 | ESR1 (0.49) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL10572667 | 0.91 | ESR1 (0.49) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL12581593 | 0.89 | NAAA (0.42) | NAAA | |
| SCHEMBL10847692 | 0.87 | CNR2 (0.44) | TLR2TLR1TLR6CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4631252-A | PHOTOGRAPHIC STABILIZERS | CIBA-GEIGY AG (CH) | 1986-12-23 | — | — | US | disclosed |
| US-4616082-A | PHOTOGRAPHIC STABILIZERS | CIBA-GEIGY AG (CH) | 1986-10-07 | — | — | US | disclosed |
| EP-0098241-B1 | HYDROQUINONE ETHERS AND A PROCESS FOR PREPARING THEM | CIBA-GEIGY AG (CH) | 1985-10-02 | — | — | EP | disclosed |