Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10402635 | 0.76 | PTGS1 (0.39) | PTGS1PTGS2HPGDTDP1 | |
| SCHEMBL10844674 | 0.75 | NPC1 (0.36) | NPC1HPGDALDH1A1HSD17B10ALOX15 | |
| SCHEMBL11008468 | 0.66 | KDM4E (0.35) | NPC1HSD17B10POLBKDM4E | |
| SCHEMBL1001661 | 0.66 | HCAR2 (0.33) | NPC1 | |
| SCHEMBL6286259 | 0.64 | NPC1 (0.35) | NPC1ALDH1A1GPR35 | |
| SCHEMBL1752323 | 0.62 | GPR35 (0.40) | NPC1HPGDALDH1A1HSD17B10ALOX15 | |
| SCHEMBL11690283 | 0.62 | NPC1 (0.44) | NPC1HPGDALDH1A1GAAMAPK1 | |
| SCHEMBL22529335 | 0.62 | NPC1 (0.37) | NPC1MAPK1CASP1CASP7GPR35 | |
| SCHEMBL20552051 | 0.62 | PKM (0.42) | NPC1PTGS1PTGS2HPGDALDH1A1 | |
| SCHEMBL11013410 | 0.62 | NPC1 (0.36) | NPC1ALDH1A1POLBMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4616081-A | ANTIBIOTIC, BACTERICIDE WITH GOOD ABSORTION AND STABILITY | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1986-10-07 | — | — | US | disclosed |
| EP-0098609-A2 | Novel cephalosporin compounds | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1984-01-18 | — | — | EP | disclosed |