Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 5/20 | 0.57 |
| ▸ | RARB | P10826 | 5/20 | 0.57 |
| ▸ | RARG | P13631 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10844073 | 0.94 | RARA (0.66) | RARARARBRARGKMT2APKM | |
| SCHEMBL10843222 | 0.88 | RARA (0.50) | RARARARBRARGKMT2APKM | |
| SCHEMBL10845484 | 0.86 | RARB (0.53) | RARARARBRARGKMT2APKM | |
| SCHEMBL10844563 | 0.84 | RARB (0.64) | RARARARBRARGKMT2APKM | |
| SCHEMBL10844561 | 0.84 | RARB (0.64) | RARARARBRARGKMT2APKM | |
| 4-Aminophenol SCHEMBL10844782 | 0.83 | RARB (0.69) | RARARARBRARGKMT2ATTR | |
| 4-Aminophenol SCHEMBL10844788 | 0.83 | RARB (0.69) | RARARARBRARGKMT2ATTR | |
| SCHEMBL10846904 | 0.82 | RARB (0.57) | RARARARBRARGKMT2APKM | |
| SCHEMBL10842264 | 0.80 | RARB (0.63) | RARARARBRARGKMT2APKM | |
| SCHEMBL4666958 | 0.77 | RARB (0.75) | RARARARBRARGMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4578498-A | FOR SKIN DISORDERS; REDUCED TOXICITY | BASF AKTIENGESELLSCHAFT (DE) | 1986-03-25 | — | — | US | disclosed |