Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.53 |
| ▸ | RARG | P13631 | 6/20 | 0.53 |
| ▸ | RARA | P10276 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10842264 | 0.93 | RARB (0.63) | RARBRARGRARAKMT2APKM | |
| SCHEMBL10844786 | 0.86 | RARA (0.57) | RARBRARGRARAKMT2APKM | |
| SCHEMBL10851223 | 0.85 | RARB (0.56) | RARBRARGRARAKMT2APKM | |
| SCHEMBL10846782 | 0.84 | KMT2A (0.44) | RARBRARGRARAKMT2APKM | |
| 4-Aminophenol SCHEMBL10845478 | 0.81 | RARB (0.67) | RARBRARGRARACYP26A1KDM4E | |
| 4-Aminophenol SCHEMBL10845491 | 0.81 | RARB (0.67) | RARBRARGRARACYP26A1KDM4E | |
| SCHEMBL10844073 | 0.80 | RARA (0.66) | RARBRARGRARAKMT2APKM | |
| SCHEMBL11249456 | 0.79 | RARB (0.56) | RARBRARGRARACYP26A1RXRA | |
| SCHEMBL11249459 | 0.79 | RARB (0.56) | RARBRARGRARACYP26A1RXRA | |
| SCHEMBL10846904 | 0.79 | RARB (0.57) | RARBRARGRARAKMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4578498-A | FOR SKIN DISORDERS; REDUCED TOXICITY | BASF AKTIENGESELLSCHAFT (DE) | 1986-03-25 | — | — | US | disclosed |