SCHEMBL10845420

SCHEMBL10845420

CCOc1ccc(C=CC(=O)c2c(O)cc(OC)cc2OC)cc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ABCG2 Q9UNQ0 6/20 0.81
▸ NFKB1 P19838 1/20 0.77
▸ DPP4 P27487 1/20 0.77
▸ NFKB2 Q00653 1/20 0.77
▸ RELA Q04206 1/20 0.77
▸ SLC5A1 P13866 2/20 0.73
▸ SLC5A2 P31639 2/20 0.73
▸ CYP3A4 P08684 5/20 0.72
▸ MAPT P10636 4/20 0.72
▸ KMT2A Q03164 3/20 0.72
▸ TP53 P04637 2/20 0.72
▸ ATM Q13315 1/20 0.72
▸ HSD17B10 Q99714 1/20 0.72
▸ MKNK2 Q9HBH9 1/20 0.71
▸ TDP1 Q9NUW8 3/20 0.70
▸ KDM4E B2RXH2 2/20 0.70
▸ MEN1 O00255 2/20 0.70
▸ HPGD P15428 2/20 0.70
▸ MCL1 Q07820 1/20 0.70
▸ USP2 O75604 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30384297 1.00 ABCG2 (0.81) ABCG2NFKB1DPP4NFKB2RELA
SCHEMBL10845412 1.00 ABCG2 (0.81) ABCG2NFKB1DPP4NFKB2RELA
SCHEMBL30383614 0.96 ABCG2 (0.75) ABCG2NFKB1DPP4NFKB2RELA
SCHEMBL10846972 0.96 ABCG2 (0.75) ABCG2NFKB1DPP4NFKB2RELA
SCHEMBL10846967 0.96 ABCG2 (0.75) ABCG2NFKB1DPP4NFKB2RELA
SCHEMBL10844969 0.95 ABCG2 (0.73) ABCG2NFKB1DPP4NFKB2RELA
SCHEMBL8415812 0.95 ABCG2 (0.81) ABCG2NFKB1DPP4NFKB2RELA
SCHEMBL30383656 0.95 ABCG2 (0.73) ABCG2NFKB1DPP4NFKB2RELA
SCHEMBL9141918 0.95 ABCG2 (0.81) ABCG2NFKB1DPP4NFKB2RELA
SCHEMBL10844965 0.95 ABCG2 (0.73) ABCG2NFKB1DPP4NFKB2RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed
US-4605674-A VIRICIDES HOFFMANN-LA ROCHE INC. (US) 1986-08-12 — — US disclosed
US-4327088-A ANTIVIRAL AGENTS HOFFMANN-LA ROCHE INC. (US) 1982-04-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ABCG2 1606/4885NFKB1 1669/4885DPP4 4226/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885NFKB1 2437/4885DPP4 3670/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885NFKB1 2437/4885DPP4 3670/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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