SCHEMBL10846972

SCHEMBL10846972

CCOc1ccc(C=CC(=O)c2c(O)cc(OCC)cc2OC)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ABCG2 Q9UNQ0 6/20 0.75
▸ SLC5A1 P13866 2/20 0.75
▸ SLC5A2 P31639 2/20 0.75
▸ NFKB1 P19838 1/20 0.71
▸ DPP4 P27487 1/20 0.71
▸ NFKB2 Q00653 1/20 0.71
▸ RELA Q04206 1/20 0.71
▸ MAPT P10636 5/20 0.66
▸ KMT2A Q03164 4/20 0.66
▸ CYP3A4 P08684 3/20 0.66
▸ TP53 P04637 2/20 0.66
▸ ATM Q13315 1/20 0.66
▸ HSD17B10 Q99714 1/20 0.66
▸ MKNK2 Q9HBH9 1/20 0.65
▸ TDP1 Q9NUW8 3/20 0.65
▸ MEN1 O00255 3/20 0.65
▸ KDM4E B2RXH2 3/20 0.65
▸ HPGD P15428 2/20 0.65
▸ MCL1 Q07820 1/20 0.65
▸ USP2 O75604 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10846967 1.00 ABCG2 (0.75) ABCG2SLC5A1SLC5A2NFKB1DPP4
SCHEMBL30383614 1.00 ABCG2 (0.75) ABCG2SLC5A1SLC5A2NFKB1DPP4
SCHEMBL10845420 0.96 ABCG2 (0.81) ABCG2SLC5A1SLC5A2NFKB1DPP4
SCHEMBL30384297 0.96 ABCG2 (0.81) ABCG2SLC5A1SLC5A2NFKB1DPP4
SCHEMBL8415812 0.96 ABCG2 (0.81) ABCG2SLC5A1SLC5A2NFKB1DPP4
SCHEMBL9141918 0.96 ABCG2 (0.81) ABCG2SLC5A1SLC5A2NFKB1DPP4
SCHEMBL10845412 0.96 ABCG2 (0.81) ABCG2SLC5A1SLC5A2NFKB1DPP4
SCHEMBL10845017 0.93 SLC5A1 (0.79) ABCG2SLC5A1SLC5A2NFKB1DPP4
SCHEMBL30384723 0.93 SLC5A1 (0.79) ABCG2SLC5A1SLC5A2NFKB1DPP4
SCHEMBL10845023 0.93 SLC5A1 (0.79) ABCG2SLC5A1SLC5A2NFKB1DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed
US-4605674-A VIRICIDES HOFFMANN-LA ROCHE INC. (US) 1986-08-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ABCG2 1606/4885SLC5A1 3752/4885SLC5A2 4208/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885SLC5A1 4485/4885SLC5A2 4756/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885SLC5A1 4485/4885SLC5A2 4756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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