Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | APP | P05067 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 4/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CASP9 | P55211 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10845595 | 1.00 | MAPT (0.51) | MAPTAPPMEN1HPGDKMT2A | |
| SCHEMBL10848662 | 0.92 | MAPT (0.44) | MAPTAPPMEN1HPGDKMT2A | |
| SCHEMBL10852784 | 0.90 | MAPT (0.50) | MAPTAPPMEN1HPGDKMT2A | |
| SCHEMBL10852779 | 0.90 | MAPT (0.50) | MAPTAPPMEN1HPGDKMT2A | |
| SCHEMBL10849419 | 0.83 | MAPT (0.51) | MAPTAPPMEN1HPGDKMT2A | |
| SCHEMBL10852100 | 0.82 | TYR (0.49) | MAPTAPPMEN1HPGDKMT2A | |
| SCHEMBL10845785 | 0.80 | TYR (0.40) | MAPTAPPMEN1KMT2ACA12 | |
| SCHEMBL10849385 | 0.79 | TYR (0.40) | MAPTAPPMEN1KMT2ACA12 | |
| Indigotindisulfonate SCHEMBL186297 | 0.77 | CA12 (0.50) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL458636 | 0.77 | CA12 (0.69) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567048-A | SULFONATED INDOXYL DERIVATIVES | PFIZER INC. (US) | 1986-01-28 | — | — | US | claimed |
| US-4567048-A | SULFONATED INDOXYL DERIVATIVES | PFIZER INC. (US) | 1986-01-28 | — | — | US | disclosed |
| US-4567048-A | SULFONATED INDOXYL DERIVATIVES | PFIZER INC. (US) | 1986-01-28 | — | — | US | disclosed |