Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.37 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.37 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 3/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10849385 | 0.96 | TYR (0.40) | TYRMAPTAPPPOLBNCOA1 | |
| SCHEMBL10845595 | 0.80 | MAPT (0.51) | TYRMAPTAPPMEN1KMT2A | |
| SCHEMBL10845588 | 0.80 | MAPT (0.51) | TYRMAPTAPPMEN1KMT2A | |
| SCHEMBL10852100 | 0.80 | TYR (0.49) | TYRMAPTAPPMEN1KMT2A | |
| SCHEMBL10848654 | 0.79 | TYR (0.57) | TYRMAPTPOLBNCOA1NCOA3 | |
| SCHEMBL10852784 | 0.76 | MAPT (0.50) | TYRMAPTAPPMEN1KMT2A | |
| SCHEMBL10852779 | 0.76 | MAPT (0.50) | TYRMAPTAPPMEN1KMT2A | |
| SCHEMBL10849419 | 0.75 | MAPT (0.51) | TYRMAPTAPPPOLBMEN1 | |
| SCHEMBL10848662 | 0.75 | MAPT (0.44) | TYRMAPTAPPMEN1KMT2A | |
| SCHEMBL10849192 | 0.75 | TYR (0.56) | TYRMAPTPOLBNCOA1NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567048-A | SULFONATED INDOXYL DERIVATIVES | PFIZER INC. (US) | 1986-01-28 | — | — | US | disclosed |