Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 3/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.41 |
| ▸ | FCER2 | P06734 | 1/20 | 0.39 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 4/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CASP9 | P55211 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10845595 | 0.82 | MAPT (0.51) | TYRMAPTMEN1KMT2AHPGD | |
| SCHEMBL10845588 | 0.82 | MAPT (0.51) | TYRMAPTMEN1KMT2AHPGD | |
| SCHEMBL10852779 | 0.81 | MAPT (0.50) | TYRMAPTMEN1KMT2AHPGD | |
| SCHEMBL10852784 | 0.81 | MAPT (0.50) | TYRMAPTMEN1KMT2AHPGD | |
| SCHEMBL10845785 | 0.80 | TYR (0.40) | TYRMAPTMEN1KMT2ACA12 | |
| SCHEMBL10849385 | 0.79 | TYR (0.40) | TYRMAPTMEN1KMT2ASYK | |
| SCHEMBL10848923 | 0.78 | MAPT (0.65) | TYRMAPTMEN1KMT2AHPGD | |
| SCHEMBL10848662 | 0.77 | MAPT (0.44) | TYRMAPTMEN1KMT2AHPGD | |
| SCHEMBL10849419 | 0.75 | MAPT (0.51) | TYRMAPTMEN1KMT2AHPGD | |
| SCHEMBL8527796 | 0.73 | SYK (0.51) | MEN1KMT2ASYKNTRK1FCER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567048-A | SULFONATED INDOXYL DERIVATIVES | PFIZER INC. (US) | 1986-01-28 | — | — | US | disclosed |