Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6953014 | 0.86 | ALDH1A1 (0.58) | FLT3ALDH1A1PTGS1PTGS2MAPK9 | |
| SCHEMBL10846686 | 0.85 | USP8 (0.56) | FLT3ALDH1A1HTTPTGS1PTGS2 | |
| SCHEMBL27825639 | 0.84 | FLT3 (0.73) | FLT3ALDH1A1HTTPTGS1PTGS2 | |
| SCHEMBL13040964 | 0.72 | POLB (0.51) | ALDH1A1HTTGAALMNAHSD17B10 | |
| SCHEMBL16305286 | 0.72 | FLT3 (0.40) | FLT3ALDH1A1PTGS1PTGS2AOC3 | |
| SCHEMBL11682185 | 0.72 | FLT3 (0.50) | FLT3ALDH1A1MAPK9MAPK10CYP1A2 | |
| SCHEMBL1395472 | 0.71 | TSHR (0.70) | FLT3ALDH1A1HTTPTGS1PTGS2 | |
| SCHEMBL28266899 | 0.71 | FLT3 (0.65) | FLT3ALDH1A1HTTPTGS1PTGS2 | |
| SCHEMBL196313 | 0.70 | CYP2A6 (0.68) | ALDH1A1HTTCYP1A2CYP3A4NPC1 | |
| SCHEMBL22778133 | 0.70 | CYP2A6 (0.68) | ALDH1A1HTTCYP1A2CYP3A4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4610994-A | 1,2,3-triazole anticonvulsant drugs | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1986-09-09 | — | — | US | disclosed |