SCHEMBL196313

SCHEMBL196313

Clc1ccc(-c2cccnc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.68
CYP1A2 P05177 2/20 0.68
ALDH1A1 P00352 2/20 0.68
CYP3A4 P08684 1/20 0.68
NPC1 O15118 1/20 0.65
RAB9A P51151 1/20 0.65
NPY5R Q15761 2/20 0.59
CYP19A1 P11511 3/20 0.57
MKNK1 Q9BUB5 3/20 0.57
MKNK2 Q9HBH9 3/20 0.57
CYP11B2 P19099 2/20 0.57
KIF11 P52732 1/20 0.57
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA9 Q16790 1/20 0.53
KDM4E B2RXH2 1/20 0.52
LMNA P02545 1/20 0.52
TP53 P04637 1/20 0.52
MAPT P10636 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30633005 1.00 CYP2A6 (0.68) CYP2A6CYP1A2ALDH1A1CYP3A4NPC1
SCHEMBL22778133 1.00 CYP2A6 (0.68) CYP2A6CYP1A2ALDH1A1CYP3A4NPC1
SCHEMBL29468035 1.00 CYP2A6 (0.68) CYP2A6CYP1A2ALDH1A1CYP3A4NPC1
SCHEMBL22137845 0.94 CYP2A6 (0.60) CYP2A6CYP1A2ALDH1A1CYP3A4NPC1
SCHEMBL24534338 0.88 CYP2A6 (0.88) CYP2A6CYP1A2ALDH1A1CYP3A4CYP19A1
SCHEMBL29360677 0.88 CYP2A6 (0.88) CYP2A6CYP1A2ALDH1A1CYP3A4CYP19A1
SCHEMBL13907273 0.88 CYP2A6 (0.88) CYP2A6CYP1A2ALDH1A1CYP3A4CYP19A1
SCHEMBL26556372 0.87 CYP11B2 (0.69) CYP2A6CYP1A2ALDH1A1CYP3A4NPC1
SCHEMBL23248728 0.87 MKNK1 (0.53) CYP2A6CYP1A2ALDH1A1CYP3A4NPC1
SCHEMBL19417424 0.84 NPC1 (0.50) CYP2A6CYP1A2ALDH1A1CYP3A4NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110894203-B Organic light-emitting compound, application thereof and organic electroluminescent device 北京绿人科技有限责任公司 2022-10-11 CN disclosed
CN-113980008-A Light extraction material, light-emitting device, display panel and display device 京东方科技集团股份有限公司 2022-01-28 CN disclosed
US-20210221784-A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PAIN UNIVERSITÉ DE STRASBOURG (FR) 2021-07-22 US disclosed
WO-2020226295-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2020-11-12 WO disclosed
CN-110894203-A Organic light-emitting compound, application thereof and organic electroluminescent device 北京绿人科技有限责任公司 2020-03-20 CN disclosed
US-10312291-B2 Photoelectric conversion device and imaging device KABUSHIKI KAISHA TOSHIBA (JP) 2019-06-04 US disclosed
CN-106661023-B Pesticidally active heterocyclic derivatives with sulphur containing substituents 先正达参股股份有限公司 2019-05-28 CN disclosed
EP-3184527-A1 2,6-DIOXO,-2,3-DIHYDRO-1H-PURINE COMPOUNDS USEFUL FOR TREATING DISORDERS RELATED TO THE ACTIVITY OF THE TRPA1 CHANNEL Hydra Biosciences, Inc. (US) 2017-06-28 EP disclosed
US-20170110517-A1 PHOTOELECTRIC CONVERSION DEVICE AND IMAGING DEVICE KABUSHIKI KAISHA TOSHIBA (JP) 2017-04-20 US disclosed
US-20170110517-A1 PHOTOELECTRIC CONVERSION DEVICE AND IMAGING DEVICE KABUSHIKI KAISHA TOSHIBA (JP) 2017-04-20 US disclosed
US-20110046336-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX SUMITOMO CHEMICAL COMPANY, LIMITED 2011-02-24 US disclosed
CN-101827854-A Transition metal complex and method for producing conjugated aromatic compound using same SUMITOMO CHEMICAL CO 2010-09-08 CN disclosed
US-20100184978-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-07-22 US disclosed
CN-101772508-A Bipyridine compound, transition metal complex, and method for production of conjugated aromatic compound using the transition metal complex SUMITOMO CHEMICAL CO 2010-07-07 CN disclosed
EP-2192124-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND WITH THE TRANSITION METAL COMPLEX Sumitomo Chemical Company, Limited (JP) 2010-06-02 EP disclosed
EP-2172470-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX Sumitomo Chemical Company, Limited (JP) 2010-04-07 EP disclosed
WO-2010010288-A2 ALKYLTHIAZOL CARBAMATE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI-AVENTIS (FR) 2010-01-28 WO disclosed
US-20090105416-A1 Synthesis of Vinylphenylpyridine and Living Anionic Polymerization GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2009-04-23 US disclosed
WO-2007129810-A1 SYNTHESIS OF VINYLPHENYLPYRIDINE AND LIVING ANIONIC POLYMERIZATION GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2007-11-15 WO disclosed
CN-1890242-A Pyrazolo and imidazo-pyrimidine derivatives HOFFMANN LA ROCHE (CH) 2007-01-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210221784-A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PAIN ACHE, TRPV1, OPRL1 CYP2A6 662/4885CYP1A2 397/4885ALDH1A1 917/4885
US-20170110517-A1 PHOTOELECTRIC CONVERSION DEVICE AND IMAGING DEVICE TRRAP, CYP1A1, CYP1B1 CYP2A6 765/4885CYP1A2 55/4885ALDH1A1 109/4885
US-20110046336-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX C9, C5, AP1M1 CYP2A6 878/4885CYP1A2 191/4885ALDH1A1 974/4885
US-20100184978-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX C9, C5, AP2M1 CYP2A6 490/4885CYP1A2 228/4885ALDH1A1 1092/4885
US-20090105416-A1 Synthesis of Vinylphenylpyridine and Living Anionic Polymerization PBRM1, MVD, PCBP1 CYP2A6 1144/4885CYP1A2 302/4885ALDH1A1 865/4885
US-10312291-B2 Photoelectric conversion device and imaging device TRRAP, CYP1A1, CYP1B1 CYP2A6 765/4885CYP1A2 55/4885ALDH1A1 109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.