Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10845673 | 0.92 | KDM4E (0.35) | P2RX3ENPP3ALPLXIAPALDH1A1 | |
| SCHEMBL10846741 | 0.90 | ALDH1A1 (0.39) | P2RX3ENPP3ALPLXIAPALDH1A1 | |
| SCHEMBL10847525 | 0.90 | ALDH1A1 (0.38) | P2RX3ALDH1A1MAPTLMNARAB9A | |
| SCHEMBL10845245 | 0.89 | MAPT (0.40) | ALDH1A1MAPTLMNARAB9AKMT2A | |
| SCHEMBL10847369 | 0.88 | P2RX3 (0.45) | P2RX3ENPP3ALPLXIAPALDH1A1 | |
| SCHEMBL10847287 | 0.88 | ALDH1A1 (0.38) | ENPP3ALPLXIAPALDH1A1MAPT | |
| SCHEMBL10848391 | 0.85 | MAPT (0.41) | P2RX3ENPP3ALPLXIAPALDH1A1 | |
| SCHEMBL10847888 | 0.85 | MAPT (0.39) | P2RX3ENPP3ALPLXIAPALDH1A1 | |
| SCHEMBL10849497 | 0.84 | P2RX3 (0.42) | P2RX3ALDH1A1MAPTLMNARAB9A | |
| SCHEMBL10846582 | 0.83 | MAPT (0.41) | P2RX3ALDH1A1MAPTLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4609660-A | Substituted carboxy-thiazolo[3,2-a]pyrimidine derivatives | FARMITALIA CARLO ERBA, S.P.A. (IT) | 1986-09-02 | — | — | US | disclosed |
| US-4558046-A | ANTIALLERGENS | FARMITALIA CARLO ERBA, S.P.A. (IT) | 1985-12-10 | — | — | US | disclosed |