Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11800462 | 0.92 | NPC1 (0.63) | MAOAMAOBNPC1RAB9AMAPT | |
| SCHEMBL27736976 | 0.87 | MAOA (0.59) | MAOAMAOBNPC1RAB9AMAPT | |
| SCHEMBL9698365 | 0.85 | MAOA (0.57) | MAOAMAOBNPC1RAB9AMAPT | |
| SCHEMBL29429630 | 0.85 | SRD5A2 (0.58) | MAOAMAOBACSL1SRD5A2 | |
| SCHEMBL6621488 | 0.85 | SRD5A2 (0.58) | MAOAMAOBACSL1SRD5A2 | |
| SCHEMBL11813212 | 0.84 | MAOA (0.55) | MAOAMAOBNPC1RAB9AMAPT | |
| SCHEMBL28014889 | 0.84 | SRD5A2 (0.57) | MAOAMAOBACSL1SRD5A2 | |
| Acetic Acid Methyl Ester SCHEMBL28693641 | 0.84 | SRD5A2 (0.50) | MAOAMAOBACSL1SRD5A2 | |
| SCHEMBL28398381 | 0.83 | ALOX5 (0.58) | MAOAMAOBRAB9AKDM4EACSL1 | |
| SCHEMBL28014981 | 0.83 | MAOA (0.53) | MAOAMAOBNPC1RAB9AACSL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4613611-A | HYPOGLYCEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1986-09-23 | — | — | US | disclosed |
| US-4536517-A | ANTIDIABETIC, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1985-08-20 | — | — | US | disclosed |