SCHEMBL10846121

SCHEMBL10846121

CN(SSN(C)C(=O)F)C(=O)F

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11188543 0.85
SCHEMBL10659833 0.80 ALDH1A1 (0.30) ALDH1A1TSHR
SCHEMBL10983952 0.79
SCHEMBL11502315 0.79
SCHEMBL11263810 0.75
SCHEMBL10842739 0.75
SCHEMBL11483593 0.73
SCHEMBL11573745 0.72 TRPA1 (0.39) ALDH1A1
SCHEMBL11502199 0.72 CES1 (0.36) ALDH1A1
SCHEMBL11571874 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4612326-A ACARICIDE, NEMATOCIDE, INSECTICIDE UNION CARBIDE CORPORATION (US) 1986-09-16 US disclosed
EP-0051990-B1 BIOLOGICALLY ACTIVE HETEROBICYCLIC HYDROXIMIDATES AND THIOLHYDROXIMIDATES AND CARBAMATE ESTER DERIVATIVES THEREOF SDS BIOTECH CORPORATION (US) 1986-01-02 EP disclosed
US-4548929-A Insecticidal and nematocidal heterobicyclic hydroximinates, thiohydroximidates, and carbamate esters, composition, and method of use thereof SDS BIOTECH CORPORATION (US) 1985-10-22 US disclosed
US-4424213-A PESTICIDES SDS BIOTECH CORPORATION (US) 1984-01-03 US disclosed
US-4413007-A INSECTICIDES, MITICIDES, NEMATOCIDES, OXIME AND BIS-(FLUOROCARBONYLAMINO) DISULFIDE REACTANTS UNION CARBIDE CORPORATION (US) 1983-11-01 US disclosed
WO-1982001650-A1 BIOLOGICALLY ACTIVE HETEROBICYCLIC HYDROXIMIDATES AND THIOLHYDROXIMIDATES AND CARBAMATE ESTER DERIVATIVES THEREOF DIAMOND SHAMROCK CORP (US) 1982-05-27 WO disclosed
EP-0051990-A1 Biologically active heterobicyclic hydroximidates and thiolhydroximidates and carbamate ester derivatives thereof SDS BIOTECH CORPORATION (US) 1982-05-19 EP disclosed
US-4327110-A Pesticidal symmetrical N-substituted bis-carbamoyloximino disulfide compounds UNION CARBIDE CORPORATION (US) 1982-04-27 US disclosed
US-4234580-A INSECTICIDES; MITACIDES UNION CARBIDE CORPORATION (US) 1980-11-18 US disclosed
US-4166864-A MITICIDES, INSECTICIDES UNION CARBIDE CORPORATION (US) 1979-09-04 US disclosed