Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | UGT1A4 | P22310 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10845012 | 0.85 | HSP90AA1 (0.46) | HSP90AA1CYP3A4ALDH1A1KMT2ACYP2C9 | |
| SCHEMBL15832956 | 0.83 | HSP90AA1 (0.49) | HSP90AA1CYP3A4ALDH1A1KMT2ACYP2C9 | |
| SCHEMBL17325283 | 0.81 | HSP90AA1 (0.50) | HSP90AA1CYP3A4ALDH1A1KMT2ACYP2C9 | |
| SCHEMBL9660975 | 0.80 | CYP3A4 (0.62) | HSP90AA1CYP3A4ALDH1A1KMT2ACYP2C9 | |
| SCHEMBL17309019 | 0.80 | HSP90AA1 (0.49) | HSP90AA1CYP3A4ALDH1A1KMT2ACYP2C9 | |
| SCHEMBL10962858 | 0.78 | ALDH1A1 (0.51) | HSP90AA1CYP3A4ALDH1A1KMT2ACYP2C9 | |
| SCHEMBL17309048 | 0.77 | CYP3A4 (0.55) | HSP90AA1CYP3A4ALDH1A1KMT2ACYP2C9 | |
| SCHEMBL15765299 | 0.75 | HSP90AA1 (0.53) | HSP90AA1CYP3A4ALDH1A1KMT2ACYP2C9 | |
| SCHEMBL18902238 | 0.72 | HSP90AA1 (0.51) | HSP90AA1CYP3A4ALDH1A1KMT2ACYP2C9 | |
| SCHEMBL15756509 | 0.72 | HSP90AA1 (0.51) | HSP90AA1CYP3A4ALDH1A1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4609668-A | AGRICULTURE | SANDOZ LTD. (CH) | 1986-09-02 | — | — | US | disclosed |