Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10845917 | 0.81 | POLB (0.38) | POLB | |
| SCHEMBL8099491 | 0.79 | — | — | |
| Bromide SCHEMBL7864614 | 0.77 | — | — | |
| SCHEMBL8100833 | 0.60 | RAB9A (0.33) | — | |
| SCHEMBL8098701 | 0.59 | ALDH1A1 (0.35) | POLB | |
| SCHEMBL8106672 | 0.59 | — | — | |
| Bromide SCHEMBL4063563 | 0.59 | RAB9A (0.32) | — | |
| Bromide SCHEMBL7867093 | 0.58 | — | — | |
| Bromide SCHEMBL4058827 | 0.58 | CHEK1 (0.34) | — | |
| SCHEMBL23815956 | 0.54 | CYP11B1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4612375-A | Substituted 4-hydrazino-pyrimides as intermediates for triazolo [4,3-c]pyrimidines | RIKER LABORATORIES, INC. (US) | 1986-09-16 | — | — | US | disclosed |
| US-4532242-A | Bronchodilator agents | RIKER LABORATORIES, INC. (US) | 1985-07-30 | — | — | US | disclosed |