Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | DBH | P09172 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | MMP9 | P14780 | 3/20 | 0.41 |
| ▸ | MMP12 | P39900 | 3/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | MMP15 | P51511 | 1/20 | 0.41 |
| ▸ | MMP16 | P51512 | 1/20 | 0.41 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22779121 | 0.82 | KDM4E (0.44) | SLC6A2SLC6A4SLC6A3KDM4EDBH | |
| SCHEMBL10121174 | 0.80 | KDM4E (0.62) | KDM4EDBHGAARECQLGSK3B | |
| SCHEMBL25834998 | 0.79 | GSK3B (0.44) | SLC6A2SLC6A4SLC6A3KDM4EDBH | |
| SCHEMBL7402177 | 0.79 | GAA (0.48) | SLC6A2SLC6A4SLC6A3KDM4EDBH | |
| SCHEMBL1226232 | 0.78 | GSK3B (0.66) | SLC6A3KDM4EDBHGAARECQL | |
| SCHEMBL12184500 | 0.78 | KDM4E (0.47) | SLC6A2SLC6A3KDM4EDBHGAA | |
| SCHEMBL10001336 | 0.77 | ACACB (0.47) | SLC6A2SLC6A4SLC6A3KDM4EGAA | |
| SCHEMBL13814902 | 0.77 | RARB (0.60) | CYP1A1CYP1A2CYP1B1RARBRARG | |
| SCHEMBL19174304 | 0.75 | CYP1A1 (0.43) | SLC6A2SLC6A4SLC6A3KDM4ECYP1A1 | |
| SCHEMBL3863011 | 0.75 | PARP10 (0.47) | SLC6A2SLC6A4SLC6A3RECQLCYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9290791-B2 | Reagents and methods for sirtuin capture | CORNELL UNIVERSITY (US) | 2016-03-22 | — | — | US | disclosed |
| US-20130065248-A1 | REAGENTS AND METHODS FOR SIRTUIN CAPTURE | CORNELL UNIVERSITY (US) | 2013-03-14 | — | — | US | disclosed |
| US-4609668-A | AGRICULTURE | SANDOZ LTD. (CH) | 1986-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065248-A1 | REAGENTS AND METHODS FOR SIRTUIN CAPTURE | SIRT3, SIRT1, SIRT2 | SLC6A2 4464/4885SLC6A4 4683/4885SLC6A3 4716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.