Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | DBH | P09172 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12418688 | 0.92 | KDM4E (0.56) | KDM4EDBHGAARECQLALDH1A1 | |
| SCHEMBL10941943 | 0.92 | KDM4E (0.56) | KDM4EDBHGAARECQLELANE | |
| SCHEMBL1878288 | 0.89 | TSHR (0.60) | KDM4EDBHGAARECQLTP53 | |
| SCHEMBL9340081 | 0.89 | GAA (0.54) | KDM4EDBHGAARECQLALDH1A1 | |
| SCHEMBL585256 | 0.89 | ALDH1A1 (0.56) | KDM4EDBHGAARECQLGSK3B | |
| SCHEMBL4378592 | 0.89 | KDM4E (0.59) | KDM4EDBHGAARECQLLMNA | |
| SCHEMBL24932160 | 0.87 | KDM4E (0.52) | KDM4EDBHGAARECQLELANE | |
| SCHEMBL204960 | 0.87 | CES2 (0.54) | KDM4EDBHGAARECQLALDH1A1 | |
| SCHEMBL4875754 | 0.87 | PARP10 (0.55) | KDM4EDBHGAARECQLTSHR | |
| SCHEMBL2625462 | 0.87 | CES2 (0.54) | KDM4EDBHGAARECQLGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230332350-A1 | DOUBLE BRAID ROPE STRUCTURE | KURARAY CO., LTD. (JP) | 2023-10-19 | — | — | US | disclosed |
| US-11713344-B2 | Acylated oxyntomodulin peptide analog | DONG-A ST CO., LTD. (KR) | 2023-08-01 | — | — | US | disclosed |
| US-11691950-B2 | Isoquinoline-steroid conjugates and uses thereof | AERIE PHARMACEUTICALS, INC. (US) | 2023-07-04 | — | — | US | disclosed |
| US-11691950-B2 | Isoquinoline-steroid conjugates and uses thereof | AERIE PHARMACEUTICALS, INC. (US) | 2023-07-04 | — | — | US | disclosed |
| US-20220315737-A1 | MIXED ESTER TEREPHTHALATE COMPOSITIONS USEFUL AS PLASTICIZERS | EASTMAN CHEMICAL COMPANY (US) | 2022-10-06 | — | — | US | disclosed |
| US-20220167976-A1 | SMALL DIAMETER FIBER BRAID WITH CENTRAL CORE MEMBER | KURARAY CO., LTD. (JP) | 2022-06-02 | — | — | US | disclosed |
| WO-2022115719-A1 | PD-L1 BINDING PEPTIDES AND PEPTIDE COMPLEXES AND METHODS OF USE THEREOF | FRED HUTCHINSON CANCER RESEARCH CENTER (US) | 2022-06-02 | — | — | WO | disclosed |
| US-11236142-B2 | Acylated oxyntomodulin peptide analog | DONG-A ST CO., LTD. (KR) | 2022-02-01 | — | — | US | disclosed |
| US-10953076-B2 | Insulin receptor partial agonists and GLP-1 analogues | MERCK SHARP & DOHME CORP. (US) | 2021-03-23 | — | — | US | disclosed |
| EP-3789426-A1 | POLYARYLETHER KETONE IMIDE SULFONE ADHESIVES | The Boeing Company (US) | 2021-03-10 | — | — | EP | disclosed |
| US-20120178666-A1 | PRODRUGS OF GUANFACINE | SHIRE LLC (US) | 2012-07-12 | — | — | US | disclosed |
| US-20120076756-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. | 2012-03-29 | — | — | US | disclosed |
| US-8101643-B2 | Benzimidazole derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2012-01-24 | — | — | US | disclosed |
| US-20110171171-A1 | BRIDGED SECONDARY AMINES AND USE THEREOF AS IAP BIR DOMAIN BINDING COMPOUNDS | AEGERA THERAPEUTICS, INC. (CA) | 2011-07-14 | — | — | US | disclosed |
| US-20110065796-A1 | PRODRUGS OF GUANFACINE | SHIRE LLC (US) | 2011-03-17 | — | — | US | disclosed |
| US-20100286186-A1 | NOVEL DICARBOXYLIC ACID LINKED AMINO ACID AND PEPTIDE PRODRUGS OF OPIOIDS AND USES THEREOF | SHIRE LLC (US) | 2010-11-11 | — | — | US | disclosed |
| US-20100260715-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2010-10-14 | — | — | US | disclosed |
| US-20100233122-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. | 2010-09-16 | — | — | US | disclosed |
| US-20100221215-A1 | LINKED DIBENZIMIDAZOLE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. | 2010-09-02 | — | — | US | disclosed |
| US-20100203012-A1 | IAP BIR DOMAIN BINDING COMPOUNDS | AEGERA THERAPEUTICS, INC. (CA) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286186-A1 | NOVEL DICARBOXYLIC ACID LINKED AMINO ACID AND PEPTIDE PRODRUGS OF OPIOIDS AND USES THEREOF | VIP, OPRL1, OPRK1 | KDM4E 1873/4885DBH 559/4885GAA 2291/4885 |
| US-20120076756-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | EIF2AK2, ZC3HAV1, HAVCR2 | KDM4E 553/4885DBH 2685/4885GAA 179/4885 |
| US-20100260715-A1 | HEPATITIS C VIRUS INHIBITORS | HAVCR2, SLC10A1, EIF2AK2 | KDM4E 1193/4885DBH 3306/4885GAA 285/4885 |
| US-20100233122-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | EIF2AK2, ZC3HAV1, HAVCR2 | KDM4E 553/4885DBH 2685/4885GAA 179/4885 |
| US-20100221215-A1 | LINKED DIBENZIMIDAZOLE DERIVATIVES | EIF2AK2, NSUN2, ZC3HAV1 | KDM4E 571/4885DBH 1713/4885GAA 433/4885 |
| US-20100203012-A1 | IAP BIR DOMAIN BINDING COMPOUNDS | BIRC5, BIRC2, BIRC3 | KDM4E 4223/4885DBH 4079/4885GAA 2614/4885 |
| US-11713344-B2 | Acylated oxyntomodulin peptide analog | GLP1R, GIPR, GPR119 | KDM4E 3039/4885DBH 1175/4885GAA 1219/4885 |
| US-10953076-B2 | Insulin receptor partial agonists and GLP-1 analogues | GLP1R, GIPR, IAPP | KDM4E 3556/4885DBH 1443/4885GAA 2026/4885 |
| US-20110171171-A1 | BRIDGED SECONDARY AMINES AND USE THEREOF AS IAP BIR DOMAIN BINDING COMPOUNDS | BIRC5, BIRC2, BIRC7 | KDM4E 3173/4885DBH 2518/4885GAA 3941/4885 |
| US-11691950-B2 | Isoquinoline-steroid conjugates and uses thereof | GRK1, TNK2, CYP11B2 | KDM4E 3367/4885DBH 1533/4885GAA 2115/4885 |
| US-11236142-B2 | Acylated oxyntomodulin peptide analog | GLP1R, GIPR, GPR119 | KDM4E 2727/4885DBH 1314/4885GAA 1494/4885 |
| US-20120178666-A1 | PRODRUGS OF GUANFACINE | DNPEP, VIP, GDA | KDM4E 1653/4885DBH 114/4885GAA 170/4885 |
| US-20110065796-A1 | PRODRUGS OF GUANFACINE | DNPEP, VIP, GDA | KDM4E 1653/4885DBH 114/4885GAA 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.