Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10847697 | 1.00 | ALDH1A1 (0.32) | ALDH1A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL10846485 | 0.86 | ALDH1A1 (0.35) | ALDH1A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL10846492 | 0.86 | ALDH1A1 (0.35) | ALDH1A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL10848517 | 0.83 | — | — | |
| SCHEMBL10848522 | 0.83 | — | — | |
| SCHEMBL16852675 | 0.62 | SMN1; SMN2 (0.36) | ALDH1A1 | |
| SCHEMBL10854100 | 0.62 | MAPT (0.38) | ALDH1A1 | |
| SCHEMBL11459269 | 0.61 | ALDH1A1 (0.61) | ALDH1A1 | |
| SCHEMBL11456166 | 0.61 | GRIN2C (0.45) | ALDH1A1 | |
| SCHEMBL8477444 | 0.61 | DAO (0.46) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4620868-A | N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-3[halo-substituted ethenyl (or propenyl)]-2-thiophenesulfonamides useful as herbicides | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1986-11-04 | — | — | US | disclosed |