Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11459269 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MAPK1LMNAMEN1KMT2A | |
| SCHEMBL8477444 | 0.79 | DAO (0.46) | ALDH1A1MAPK1LMNAMEN1KMT2A | |
| SCHEMBL11497669 | 0.69 | ALDH1A1 (0.36) | ALDH1A1MAPK1LMNAMEN1KMT2A | |
| SCHEMBL14018717 | 0.68 | ALDH1A1 (0.47) | GRIN2CALDH1A1MAPK1LMNAMEN1 | |
| SCHEMBL11497615 | 0.67 | GRIN2C (0.40) | GRIN2CALDH1A1MAPK1LMNAMEN1 | |
| SCHEMBL3663408 | 0.66 | DAO (0.57) | GRIN2CALDH1A1MAPK1LMNAMEN1 | |
| SCHEMBL2778266 | 0.66 | GAA (0.65) | GRIN2CALDH1A1MAPK1LMNAMEN1 | |
| SCHEMBL3664149 | 0.66 | ALDH1A1 (0.46) | GRIN2CALDH1A1MAPK1LMNAMEN1 | |
| SCHEMBL11459274 | 0.66 | L3MBTL1 (0.51) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL710923 | 0.66 | AGTR2 (0.32) | ALDH1A1MAPK1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4233333-A | 4,5-Dimethyl-thieno[3,2-d]isothiazolo-3(2H)-one-1,1-dioxides, compositions, and methods of use as a sweetener | BOEHRINGER INGELHEIM GMBH (DE) | 1980-11-11 | — | — | US | disclosed |