SCHEMBL10847985

SCHEMBL10847985

Oc1ccc(Oc2ncc(Br)cc2Cl)cc1

nearest known ligand 0.71

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.71
SMN1; SMN2 Q16637 3/20 0.57
LMNA P02545 2/20 0.57
CYP2C9 P11712 1/20 0.57
TSHR P16473 1/20 0.57
APEX1 P27695 1/20 0.57
RAB9A P51151 1/20 0.45
LIPE Q05469 4/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
LTA4H P09960 1/20 0.39
BCHE P06276 1/20 0.39
F2 P00734 1/20 0.39
F10 P00742 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8684251 0.84 SMN1; SMN2 (0.57) MAPK1SMN1; SMN2LMNACYP2C9TSHR
SCHEMBL15382927 0.84 MAPK1 (0.71) MAPK1SMN1; SMN2LMNACYP2C9TSHR
SCHEMBL5647172 0.83 MAPK1 (1.00) MAPK1SMN1; SMN2LMNACYP2C9TSHR
SCHEMBL10854830 0.82 MAPK1 (0.97) MAPK1SMN1; SMN2LMNACYP2C9TSHR
SCHEMBL10969136 0.81 MAPK1 (0.71) MAPK1SMN1; SMN2LMNACYP2C9TSHR
SCHEMBL8689392 0.78 SMN1; SMN2 (0.48) MAPK1SMN1; SMN2LMNACYP2C9TSHR
SCHEMBL5687596 0.77 RAB9A (0.73) MAPK1SMN1; SMN2LMNARAB9ALIPE
SCHEMBL31251923 0.77 RAB9A (0.73) MAPK1SMN1; SMN2LMNARAB9ALIPE
SCHEMBL10852518 0.77 L3MBTL1 (0.53) MAPK1SMN1; SMN2LMNACYP2C9TSHR
SCHEMBL8689394 0.77 L3MBTL1 (0.53) MAPK1SMN1; SMN2LMNACYP2C9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4584396-A Substituted phenoxypropionates and herbicidal compositions NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1986-04-22 US disclosed
EP-0068260-B1 SUBSTITUTED PHENOXYPROPIONATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1986-03-05 EP disclosed
EP-0086392-B1 HERBICIDAL AGENT CONTAINING METAMITRON IN COMBINATION WITH CERTAIN PHENOXYPROPIONIC-ACID ESTERS BAYER AG (DE) 1985-08-21 EP disclosed
US-4441913-A PRE- AND POST-EMERGENCE NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1984-04-10 US disclosed
EP-0086392-A1 Herbicidal agent containing metamitron in combination with certain phenoxypropionic-acid esters BAYER AG (DE) 1983-08-24 EP disclosed
EP-0084819-A2 Herbicidal agents containing methabenzthiazuron in combination with certain phenoxypropionic acid esters BAYER AG (DE) 1983-08-03 EP disclosed
EP-0068260-A2 Substituted phenoxypropionates, process for their preparation and their use as herbicides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1983-01-05 EP disclosed