Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 19/20 | 0.58 |
| ▸ | ACE2 | Q9BYF1 | 10/20 | 0.55 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10664993 | 0.88 | ACE (0.73) | ACEACE2 | |
| SCHEMBL7408089 | 0.79 | ACE (0.59) | ACEACE2 | |
| SCHEMBL7468516 | 0.79 | ACE (0.59) | ACEACE2 | |
| SCHEMBL10664899 | 0.78 | ACE (0.72) | ACEACE2 | |
| SCHEMBL9791962 | 0.78 | ACE (0.59) | ACEACE2 | |
| SCHEMBL10847107 | 0.78 | ACE (0.72) | ACEACE2 | |
| SCHEMBL7412359 | 0.77 | ACE (0.56) | ACEACE2 | |
| SCHEMBL7408382 | 0.76 | ACE (0.65) | ACEACE2 | |
| SCHEMBL10459532 | 0.76 | ACE (0.65) | ACEACE2 | |
| SCHEMBL10669144 | 0.76 | ACE (0.58) | ACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4604402-A | HYPOTENSIVE AGNETS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-05 | — | — | US | disclosed |