Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL10851836 | 0.90 | LMNA (0.46) | KMT2AALDH1A1TSHRHSD17B10TP53 | |
| Propane SCHEMBL10852960 | 0.89 | KMT2A (0.34) | KMT2AALDH1A1TSHRHSD17B10TP53 | |
| Propane SCHEMBL10857479 | 0.89 | LMNA (0.32) | KMT2AALDH1A1TSHRHSD17B10TP53 | |
| Ethane SCHEMBL10922589 | 0.88 | LMNA (0.47) | KMT2AALDH1A1TSHRHSD17B10TP53 | |
| Propane SCHEMBL10854163 | 0.88 | LMNA (0.47) | KMT2AALDH1A1TSHRHSD17B10TP53 | |
| Propane SCHEMBL10850051 | 0.88 | ALDH1A1 (0.40) | ALDH1A1TSHRHSD17B10TP53CYP3A4 | |
| Propane SCHEMBL10857615 | 0.86 | CYP1A2 (0.36) | KMT2AALDH1A1TSHRHSD17B10TP53 | |
| Butane SCHEMBL10852232 | 0.85 | LMNA (0.45) | KMT2AALDH1A1TSHRHSD17B10TP53 | |
| Methane SCHEMBL10919631 | 0.85 | LMNA (0.47) | KMT2AALDH1A1TSHRHSD17B10TP53 | |
| SCHEMBL8345854 | 0.84 | MEN1 (0.42) | KMT2AALDH1A1TSHRHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4584295-A | Pyrimidylmethyl thiophosphorus esters useful for the control of insects, mites and nematodes | HOFFMANN-LA ROCHE INC. (US) | 1986-04-22 | — | — | US | disclosed |