Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12856309 | 0.84 | PDE2A (0.50) | PDE2AMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL14996620 | 0.84 | PDE2A (0.50) | PDE2AMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL24106554 | 0.83 | PDE2A (0.53) | PDE2AMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL12856451 | 0.81 | PDE2A (0.47) | PDE2AMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL12859563 | 0.81 | PDE2A (0.47) | PDE2AMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL10957006 | 0.81 | PDE2A (0.44) | PDE2AMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL10922604 | 0.80 | MAPT (0.44) | PDE2AMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL5598919 | 0.80 | MAPT (0.65) | PDE2AMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL10793219 | 0.80 | MAPT (0.65) | PDE2AMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL31070905 | 0.80 | MAPT (0.65) | PDE2AMAPTALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4493844-A | Insecticidal 2,2'-bridged(1,1'-biphenyl)-3-ylmethyl carboxamides | FMC CORPORATION (US) | 1985-01-15 | — | — | US | claimed |
| US-4487778-A | Insecticidal esters derived from benzocycloalkane-thiophenemethyl compounds | FMC CORPORATION (US) | 1984-12-11 | — | — | US | claimed |
| US-4451484-A | ALSO MITICIDES | FMC CORPORATION (US) | 1984-05-29 | — | — | US | claimed |
| US-4605748-A | INSECTICIDES, MITICIDES | FMC CORPORATION (US) | 1986-08-12 | — | — | US | disclosed |
| US-4596892-A | 6,7-Dihydro-5H-dibenzo(a,c)cyclohepten-4-methanoamine | FMC CORPORATION (US) | 1986-06-24 | — | — | US | disclosed |
| US-4507317-A | Acaricidal 2,2'-bridged[1,1'-biphenyl]-3-ylmethyl esters | FMC CORPORATION (US) | 1985-03-26 | — | — | US | disclosed |
| US-4493844-A | Insecticidal 2,2'-bridged(1,1'-biphenyl)-3-ylmethyl carboxamides | FMC CORPORATION (US) | 1985-01-15 | — | — | US | disclosed |
| US-4487778-A | Insecticidal esters derived from benzocycloalkane-thiophenemethyl compounds | FMC CORPORATION (US) | 1984-12-11 | — | — | US | disclosed |
| US-4451484-A | ALSO MITICIDES | FMC CORPORATION (US) | 1984-05-29 | — | — | US | disclosed |
| US-4433182-A | Insecticidal 2,2'-bridged[1,1'-biphenyl]-3-ylmethyl esters | FMC CORPORATION (US) | 1984-02-21 | — | — | US | disclosed |