Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14996620 | 0.90 | PDE2A (0.50) | PDE2AMAPTALDH1A1LMNANPSR1 | |
| SCHEMBL12856309 | 0.86 | PDE2A (0.50) | PDE2AMAPTALDH1A1LMNANPSR1 | |
| SCHEMBL3232155 | 0.86 | LMNA (0.58) | PDE2AMAPTALDH1A1LMNANPSR1 | |
| Ammonia Solution, Strong SCHEMBL3234716 | 0.84 | LMNA (0.57) | PDE2AMAPTALDH1A1LMNANPSR1 | |
| SCHEMBL20393776 | 0.84 | CYP2C19 (0.37) | PDE2AMAPTALDH1A1LMNANPSR1 | |
| SCHEMBL10848846 | 0.83 | PDE2A (0.47) | PDE2AMAPTALDH1A1LMNANPSR1 | |
| SCHEMBL12859563 | 0.83 | PDE2A (0.47) | PDE2AMAPTALDH1A1LMNANPSR1 | |
| SCHEMBL12856451 | 0.83 | PDE2A (0.47) | PDE2AMAPTALDH1A1LMNANPSR1 | |
| SCHEMBL10954628 | 0.82 | PDE2A (0.46) | PDE2AMAPTALDH1A1LMNANPSR1 | |
| SCHEMBL13483717 | 0.81 | KIF11 (0.43) | PDE2AMAPTALDH1A1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210386065-A1 | MIXTURE OF MECTINS AND PYRETHROIDS AND USES THEREOF | VALENT BIOSCIENCES LLC | 2021-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210386065-A1 | MIXTURE OF MECTINS AND PYRETHROIDS AND USES THEREOF | ACHE, DDT, PTMS | PDE2A 625/4885MAPT 2689/4885ALDH1A1 4548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.