Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28265559 | 0.85 | KDM4E (0.63) | HSD17B10KDM4EALDH1A1NPC1TP53 | |
| SCHEMBL28265572 | 0.85 | KDM4E (0.75) | HSD17B10KDM4EALDH1A1NPC1TP53 | |
| SCHEMBL11645317 | 0.85 | HSD17B10 (0.57) | HSD17B10KDM4EALDH1A1NPC1TP53 | |
| SCHEMBL376001 | 0.84 | ALDH1A1 (0.64) | HSD17B10KDM4EALDH1A1NPC1TP53 | |
| SCHEMBL2998669 | 0.83 | NPC1 (0.71) | HSD17B10KDM4EALDH1A1NPC1TP53 | |
| SCHEMBL28267022 | 0.82 | KDM4E (0.56) | HSD17B10KDM4EALDH1A1NPC1TP53 | |
| SCHEMBL12076741 | 0.82 | ALDH1A1 (0.62) | HSD17B10KDM4EALDH1A1NPC1TP53 | |
| SCHEMBL12376180 | 0.80 | ALDH1A1 (0.60) | HSD17B10KDM4EALDH1A1NPC1TP53 | |
| SCHEMBL28265565 | 0.80 | KDM4E (0.54) | HSD17B10KDM4EALDH1A1NPC1TP53 | |
| SCHEMBL5792476 | 0.80 | SMN1; SMN2 (0.65) | HSD17B10KDM4EALDH1A1NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116942-B1 | METHOD TO PREPARE 4,4'-BIS-BENZ-OX(THI, -IMID)-AZOL-2-YL STILBENES | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-07-16 | — | — | EP | disclosed |
| US-4585875-A | FROM 4-CHLOROMETHYL BENZOIC IMIDO ESTER | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-04-29 | — | — | US | disclosed |
| EP-0116942-A1 | Method to prepare 4,4'-bis-benz-ox(thi, -imid)-azol-2-yl stilbenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-08-29 | — | — | EP | disclosed |