Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5182011 | 0.86 | NPC1 (0.76) | NPC1KDM4EALDH1A1TP53HPGD | |
| SCHEMBL31170 | 0.86 | NPC1 (0.81) | NPC1KDM4EALDH1A1TP53HPGD | |
| Methane SCHEMBL29265168 | 0.84 | NPC1 (0.79) | NPC1KDM4EALDH1A1TP53HPGD | |
| SCHEMBL31476 | 0.84 | NPC1 (0.79) | NPC1KDM4EALDH1A1TP53HPGD | |
| SCHEMBL3421338 | 0.83 | NPC1 (0.71) | NPC1KDM4EALDH1A1TP53HPGD | |
| SCHEMBL3373866 | 0.83 | NPC1 (0.71) | NPC1KDM4EALDH1A1TP53HPGD | |
| SCHEMBL11701224 | 0.83 | NPC1 (0.71) | NPC1KDM4EALDH1A1TP53HPGD | |
| SCHEMBL4907802 | 0.83 | NPC1 (0.71) | NPC1KDM4EALDH1A1TP53HPGD | |
| SCHEMBL1660541 | 0.83 | NPC1 (1.00) | NPC1KDM4EALDH1A1TP53HPGD | |
| SCHEMBL10849065 | 0.83 | HSD17B10 (0.57) | NPC1KDM4EALDH1A1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114933440-B | Pervious concrete additive and pervious concrete | 宁波新力建材科技有限公司 | 2022-11-08 | — | — | CN | claimed |
| CN-114933440-A | Pervious concrete additive and pervious concrete | 宁波新力建材科技有限公司 | 2022-08-23 | — | — | CN | claimed |
| US-4264709-A | ETHYLENICALLY UNSATURATED MONOMERS | EASTMAN KODAK COMPANY (US) | 1981-04-28 | — | — | US | claimed |
| CN-114933440-B | Pervious concrete additive and pervious concrete | 宁波新力建材科技有限公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-114933440-B | Pervious concrete additive and pervious concrete | 宁波新力建材科技有限公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-114933440-A | Pervious concrete additive and pervious concrete | 宁波新力建材科技有限公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-114933440-A | Pervious concrete additive and pervious concrete | 宁波新力建材科技有限公司 | 2022-08-23 | — | — | CN | disclosed |
| US-10053428-B2 | 5-aminotetrahydroquinoline-2-carboxylic acids and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-08-21 | — | — | US | disclosed |
| US-20170260139-A1 | NOVEL 5-AMINOTETRAHYDROQUINOLINE-2-CARBOXYLIC ACIDS AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-14 | — | — | US | disclosed |
| US-9695331-B2 | Silicon-containing (meth) acrylate compounds | ARKEMA FRANCE (FR) | 2017-07-04 | — | — | US | disclosed |
| EP-2875003-B1 | NEW 5-AMINOTETRAHYDROQUINOLINE-2-CARBOXYLIC ACIDS UND THEIR USE | Bayer Pharma AG (DE) | 2016-11-16 | — | — | EP | disclosed |
| WO-2000044732-A1 | PROCESS FOR THE PREPARATION OF 4,4'-BIS(2-BENZOXAZOLYL)STILBENES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-08-03 | — | — | WO | disclosed |
| US-4585875-A | FROM 4-CHLOROMETHYL BENZOIC IMIDO ESTER | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-04-29 | — | — | US | disclosed |
| EP-0019182-B1 | BENZOFURAN DERIVATIVES AND THEIR USE AS OPTICAL BRIGHTENERS | BAYER AG (DE) | 1982-07-07 | — | — | EP | disclosed |
| US-4289887-A | OPTICAL BRIGHTENERS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-15 | — | — | US | disclosed |
| EP-0033459-A1 | Benzoxazolylstilbenes, processes for their production and their use as optical brighteners | BAYER AG (DE) | 1981-08-12 | — | — | EP | disclosed |
| US-4264709-A | ETHYLENICALLY UNSATURATED MONOMERS | EASTMAN KODAK COMPANY (US) | 1981-04-28 | — | — | US | disclosed |
| EP-0019182-A1 | Benzofuran derivatives and their use as optical brighteners | BAYER AG (DE) | 1980-11-26 | — | — | EP | disclosed |
| US-4158658-A | Bichromophoric benzoxazole-styrene ultraviolet stabilizers and their use in organic compositions | EASTMAN KODAK COMPANY (US) | 1979-06-19 | — | — | US | disclosed |
| US-4075162-A | BICHROMOPHORIC BENZOXAZOLE-STYRENE ULTRAVIOLET STABILIZERS AND THEIR USE IN ORGANIC COMPOSITIONS | EASTMAN KODAK COMPANY (US) | 1978-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10053428-B2 | 5-aminotetrahydroquinoline-2-carboxylic acids and their use | TNNT2, TNNI3, FABP3 | NPC1 1352/4885KDM4E 3842/4885ALDH1A1 684/4885 |
| US-20170260139-A1 | NOVEL 5-AMINOTETRAHYDROQUINOLINE-2-CARBOXYLIC ACIDS AND THEIR USE | TNNT2, TNNI3, FABP3 | NPC1 1442/4885KDM4E 3868/4885ALDH1A1 679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.