Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10886723 | 0.88 | ALDH1A1 (0.50) | HPGDALDH1A1MAPTSMN1; SMN2PDE3B | |
| SCHEMBL10888365 | 0.86 | PDE3B (0.47) | ALDH1A1MAPTSMN1; SMN2MAPK1PDE3B | |
| SCHEMBL10887732 | 0.85 | ALDH1A1 (0.48) | HPGDALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL10886795 | 0.85 | PDE3B (0.49) | ALDH1A1MAPTSMN1; SMN2MAPK1PDE3B | |
| SCHEMBL10890398 | 0.85 | PDE3B (0.46) | ALDH1A1MAPTSMN1; SMN2MAPK1PDE3B | |
| Hydrochloric Acid SCHEMBL10889345 | 0.84 | PDE3B (0.45) | ALDH1A1MAPTSMN1; SMN2MAPK1PDE3B | |
| SCHEMBL10639060 | 0.84 | TP53 (0.56) | HPGDALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL10891327 | 0.84 | PDE3B (0.45) | ALDH1A1MAPTSMN1; SMN2MAPK1PDE3B | |
| SCHEMBL10890051 | 0.83 | TAAR1 (0.46) | ALDH1A1MAPTSMN1; SMN2MAPK1PDE3B | |
| SCHEMBL10887156 | 0.83 | PDE3B (0.44) | HPGDALDH1A1MAPTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4618610-A | Triazine derivatives, and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-21 | — | — | US | disclosed |
| EP-0123254-A1 | Triazine derivatives, processes for preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-31 | — | — | EP | disclosed |