Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 6/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10889345 | 0.99 | PDE3B (0.45) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10886795 | 0.90 | PDE3B (0.49) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10888365 | 0.88 | PDE3B (0.47) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10887732 | 0.87 | ALDH1A1 (0.48) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10639060 | 0.86 | TP53 (0.56) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10891327 | 0.86 | PDE3B (0.45) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10887156 | 0.85 | PDE3B (0.44) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10849499 | 0.85 | HPGD (0.48) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10890051 | 0.85 | TAAR1 (0.46) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10636413 | 0.84 | PDE3B (0.64) | PDE3BPDE3APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4616015-A | HYPOTENSIVE AGENT, ANTULCER AGENT, ANTICOAGULANT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-07 | — | — | US | claimed |
| EP-0122627-A2 | Triazine derivatives, processes for preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-24 | — | — | EP | claimed |