Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | HPGD | P15428 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040427 | 0.84 | KDM4E (0.41) | KDM4EADRB2GRM6ALDH1A1HPGD | |
| SCHEMBL31371225 | 0.79 | KDM4E (0.38) | KDM4EADRB2RXFP1SMN1; SMN2GRM6 | |
| SCHEMBL11039790 | 0.76 | KDM4E (0.41) | KDM4EGRM6ALDH1A1HPGDLMNA | |
| SCHEMBL10860704 | 0.74 | KMT2A (0.35) | KDM4ERXFP1SMN1; SMN2GRM6ALDH1A1 | |
| SCHEMBL31392497 | 0.72 | ADRB2 (0.44) | KDM4EADRB2ALDH1A1GAAHTT | |
| SCHEMBL4632655 | 0.72 | ATM (0.40) | LMNATSHRMEN1KMT2A | |
| SCHEMBL18330714 | 0.72 | KDM4E (0.41) | KDM4EGRM6ALDH1A1HPGDLMNA | |
| SCHEMBL10856905 | 0.72 | KDM4E (0.43) | KDM4ESMN1; SMN2GRM6ALDH1A1HPGD | |
| SCHEMBL25982008 | 0.71 | TSHR (0.38) | KDM4EADRB2GRM6ALDH1A1LMNA | |
| SCHEMBL11410997 | 0.70 | KDM4E (0.37) | KDM4EADRB2ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4582898-A | BLUE SHADES ON POLYESTER | BAYER AKTIENGESELLSCHAFT (DE) | 1986-04-15 | — | — | US | disclosed |
| EP-0095638-B1 | 2,6-DICYANOANILINES | BAYER AG (DE) | 1985-08-28 | — | — | EP | disclosed |
| EP-0095638-A1 | 2,6-Dicyanoanilines | BAYER AG (DE) | 1983-12-07 | — | — | EP | disclosed |