Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NEK2 | P51955 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10851986 | 0.84 | KDM4E (0.39) | KDM4EGRM6TSHRALDH1A1MAPT | |
| SCHEMBL11039790 | 0.83 | KDM4E (0.41) | KDM4EGRM6TSHRALDH1A1MAPT | |
| SCHEMBL5211581 | 0.83 | KDM4E (0.44) | KDM4EGRM6TSHRNEK2DYRK1A | |
| SCHEMBL25982008 | 0.83 | TSHR (0.38) | KDM4EGRM6TSHRALDH1A1MAPT | |
| SCHEMBL10872733 | 0.80 | TSHR (0.39) | KDM4EGRM6TSHRNEK2DYRK1A | |
| SCHEMBL18330714 | 0.79 | KDM4E (0.41) | KDM4EGRM6TSHRALDH1A1MAPT | |
| SCHEMBL10860704 | 0.77 | KMT2A (0.35) | KDM4EGRM6TSHRALDH1A1HTT | |
| SCHEMBL11410997 | 0.77 | KDM4E (0.37) | KDM4ETSHRALDH1A1MAPTHTT | |
| SCHEMBL7152228 | 0.76 | TSHR (0.39) | KDM4EGRM6TSHRALDH1A1MAPT | |
| SCHEMBL16122686 | 0.75 | TSHR (0.35) | KDM4ETSHRALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9540350-B2 | 1-substituted, 4-(substituted phenoxymethyl)-1,2,3-triazole compounds with antifungal properties and methods for preparation thereof | FDC LIMITED (IN) | 2017-01-10 | — | — | US | disclosed |
| US-20160009692-A1 | 1-SUBSTITUTED, 4-(SUBSTITUTED PHENOXYMETHYL)-1,2,3-TRIAZOLE COMPOUNDS WITH ANTIFUNGAL PROPERTIES AND METHODS FOR PREPARATION THEREOF | FDC LIMITED (IN) | 2016-01-14 | — | — | US | disclosed |
| WO-2014132267-A1 | 1-SUBSTITUTED, 4-(SUBSTITUTED PHENOXYMETHYL)-1,2,3-TRIAZOLE COMPOUNDS WITH ANTIFUNGAL PROPERTIES AND METHODS FOR PREPARATION THEREOF | FDC LIMITED (IN) | 2014-09-04 | — | — | WO | disclosed |
| WO-2014073003-A1 | SINGLE-STEP PROCESS FOR THE PREPARATION OF ARYL OLEFINS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-05-15 | — | — | WO | disclosed |
| US-4456668-A | DYE BLEACH, TEXTILE DYES | CIBA GEIGY AG (CH) | 1984-06-26 | — | — | US | disclosed |
| EP-0040171-B1 | AZO DYESTUFFS, METHODS FOR THEIR PREPARATION AND THEIR USE AS COLOURING AGENTS IN THE SILVER DYESTUFF BLEACHING PROCESS | CIBA-GEIGY AG (CH) | 1984-03-21 | — | — | EP | disclosed |
| US-4409143-A | TEXTILES, PHOTOGRAPHY | CIBA-GEIGY AG (CH) | 1983-10-11 | — | — | US | disclosed |
| EP-0040171-A2 | Azo dyestuffs, methods for their preparation and their use as colouring agents in the silver dyestuff bleaching process | CIBA-GEIGY AG (CH) | 1981-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009692-A1 | 1-SUBSTITUTED, 4-(SUBSTITUTED PHENOXYMETHYL)-1,2,3-TRIAZOLE COMPOUNDS WITH ANTIFUNGAL PROPERTIES AND METHODS FOR PREPARATION THEREOF | ERG28, CYP51A1, CYP2E1 | KDM4E 1698/4885GRM6 4713/4885TSHR 4119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.