Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10848578 | 0.98 | MAOA (0.50) | MAOAMAOBACSL1SRD5A2ALOX5 | |
| SCHEMBL10845978 | 0.85 | MAOA (0.45) | MAOAMAOBACSL1SRD5A2ALOX5 | |
| SCHEMBL27736976 | 0.84 | MAOA (0.59) | MAOAMAOBACSL1SRD5A2ALOX5 | |
| SCHEMBL6621488 | 0.83 | SRD5A2 (0.58) | MAOAMAOBACSL1SRD5A2ALOX5 | |
| SCHEMBL9698365 | 0.83 | MAOA (0.57) | MAOAMAOBACSL1SRD5A2ALOX5 | |
| SCHEMBL29429630 | 0.83 | SRD5A2 (0.58) | MAOAMAOBACSL1SRD5A2ALOX5 | |
| SCHEMBL28014889 | 0.81 | SRD5A2 (0.57) | MAOAMAOBACSL1SRD5A2ALOX5 | |
| SCHEMBL10845751 | 0.81 | MAOA (0.55) | MAOAMAOBACSL1SRD5A2NPC1 | |
| SCHEMBL28014981 | 0.80 | MAOA (0.53) | MAOAMAOBACSL1SRD5A2ALOX5 | |
| SCHEMBL14124825 | 0.78 | SRD5A2 (0.51) | MAOAMAOBACSL1SRD5A2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4613611-A | HYPOGLYCEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1986-09-23 | — | — | US | claimed |
| US-4613611-A | HYPOGLYCEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1986-09-23 | — | — | US | disclosed |