Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27758385 | 0.88 | MAPT (0.50) | MAPTMEN1KMT2APOLBMCL1 | |
| SCHEMBL19030215 | 0.82 | MAPT (0.41) | MAPTMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL14174533 | 0.82 | ALDH1A1 (0.48) | MAPTMEN1KMT2APOLBMCL1 | |
| SCHEMBL27732031 | 0.81 | MAPT (0.43) | MAPTMEN1KMT2APOLBMCL1 | |
| SCHEMBL27732012 | 0.79 | MAPT (0.41) | MAPTMEN1KMT2APOLBMCL1 | |
| SCHEMBL303812 | 0.79 | MAPT (0.44) | MAPTMEN1KMT2APOLBMCL1 | |
| SCHEMBL31451466 | 0.79 | ALDH1A1 (0.48) | MAPTMEN1KMT2APOLBMCL1 | |
| SCHEMBL31000979 | 0.79 | MAPT (1.00) | MAPTMEN1KMT2APOLBMCL1 | |
| SCHEMBL1624146 | 0.79 | MAPT (1.00) | MAPTMEN1KMT2APOLBMCL1 | |
| SCHEMBL25387147 | 0.77 | MAPT (0.45) | MAPTMEN1KMT2APOLBMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 407 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972044-A | Composition and method for dyeing keratin fibers | WELLA AG (DE) | 1999-10-26 | — | — | US | claimed |
| EP-0867170-A2 | Composition and method for dyeing keratin fibres | Wella Aktiengesellschaft (DE) | 1998-09-30 | — | — | EP | claimed |
| US-11298304-B2 | Two component hair treatment kit comprising a hair coloring cream and a developer composition comprising a specific tensioactive compound | LABORATOIRE BIOSTHÉTIQUE KOSMETIK GMBH & CO. KG (DE) | 2022-04-12 | — | — | US | disclosed |
| US-20210128427-A1 | TWO COMPONENT HAIR TREATMENT KIT COMPRISING A HAIR COLORING CREAM AND A DEVELOPER COMPOSITION COMPRISING A SPECIFIC TENSIOACTIVE COMPOUND | LABORATOIRE BIOSTHÉTIQUE KOSMETIK GMBH & CO. KG (DE) | 2021-05-06 | — | — | US | disclosed |
| EP-3773435-A1 | TWO COMPONENT HAIR TREATMENT KIT COMPRISING A HAIR COLORING CREAM AND A DEVELOPER COMPOSITION COMPRISING A SPECIFIC TENSIOACTIVE COMPOUND | Laboratoire Biosthetique Kosmetik GmbH&Co. KG (DE) | 2021-02-17 | — | — | EP | disclosed |
| CN-111936110-A | Two-component hair treatment kit comprising a hair dye cream and a developer composition comprising specific surface-active compounds | 科斯梅蒂克生物技术实验室有限公司 | 2020-11-13 | — | — | CN | disclosed |
| CN-106794127-B | Permanent hair dye based on an emulsion-like vehicle and a combination of tris (hydroxymethyl) aminomethane, at least one amino acid and an oxidation dye | HCT-头发化妆品技术股份公司 | 2020-05-29 | — | — | CN | disclosed |
| US-10456341-B2 | Compositions and methods for simultaneous reshaping and direct coloring of hair | ALFA PARF GROUP S.P.A. (IT) | 2019-10-29 | — | — | US | disclosed |
| EP-2930126-B1 | Fashionable aerosol dye | HENKEL AG & CO KGAA (DE) | 2019-10-09 | — | — | EP | disclosed |
| WO-2019185127-A1 | TWO COMPONENT HAIR TREATMENT KIT COMPRISING A HAIR COLORING CREAM AND A DEVELOPER COMPOSITION COMPRISING A SPECIFIC TENSIOACTIVE COMPOUND | HCT - HAIR COSMETIC TECHNOLOGY AG (CH) | 2019-10-03 | — | — | WO | disclosed |
| EP-2979683-B1 | Permanent hair colorants based on a cream-like carrier and a combination of tris(hydroxymethyl)aminomethane, at least an amino acid and an oxidative dye | HCT HAIR COSMETIC TECH AG (CH) | 2019-07-24 | — | — | EP | disclosed |
| EP-0867171-A2 | Powder composition for the preparation of gels comprising a methyl hydroxyalkyl cellulose | Wella Aktiengesellschaft (DE) | 1998-09-30 | — | — | EP | disclosed |
| WO-1998023247-A1 | AGENT FOR DYEING AND DECOLORIZING FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 1998-06-04 | — | — | WO | disclosed |
| WO-1998022078-A1 | AGENTS FOR DYING AND DECOLORIZING FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 1998-05-28 | — | — | WO | disclosed |
| EP-0592396-B1 | BENZOXAZINE DYES | BRISTOL MYERS SQUIBB CO (US) | 1997-04-16 | — | — | EP | disclosed |
| EP-0592396-A1 | BENZOXAZINE DYES. | BRISTOL MYERS SQUIBB CO (US) | 1994-04-20 | — | — | EP | disclosed |
| EP-0592396-A4 | BENZOXAZINE DYES. | BRISTOL MYERS SQUIBB CO (US) | 1992-09-28 | — | — | EP | disclosed |
| US-5118323-A | Hair dyes | CLAIROL, INC. | 1992-06-02 | — | — | US | disclosed |
| US-5055110-A | Hair dyes | CLAIROL INCORPORATED (US) | 1991-10-08 | — | — | US | disclosed |
| WO-1991007394-A1 | BENZOXAZINE DYES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210128427-A1 | TWO COMPONENT HAIR TREATMENT KIT COMPRISING A HAIR COLORING CREAM AND A DEVELOPER COMPOSITION COMPRISING A SPECIFIC TENSIOACTIVE COMPOUND | KRT18, KIT, PRKDC | MAPT 1857/4885MEN1 4124/4885KMT2A 1061/4885 |
| US-11298304-B2 | Two component hair treatment kit comprising a hair coloring cream and a developer composition comprising a specific tensioactive compound | KRT18, KIT, PRKDC | MAPT 1857/4885MEN1 4124/4885KMT2A 1061/4885 |
| US-10456341-B2 | Compositions and methods for simultaneous reshaping and direct coloring of hair | GRHPR, DAO, ALPG | MAPT 2959/4885MEN1 1382/4885KMT2A 1630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.